Eric V Shusta
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Explore the profile of Eric V Shusta including associated specialties, affiliations and a list of published articles.
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110
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4056
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Recent Articles
1.
Foreman K, Gastfriend B, Katt M, Palecek S, Shusta E
Biomolecules
. 2025 Feb;
15(2).
PMID: 40001496
Endothelial cells throughout the body sense blood flow, eliciting transcriptional and phenotypic responses. The brain endothelium, known as the blood-brain barrier (BBB), possesses unique barrier and transport properties, which are...
2.
Appelt E, Thoden J, Dancy C, Bachmeier H, Gehrke S, Staffenson M, et al.
Biotechnol Prog
. 2025 Jan;
:e3530.
PMID: 39846486
Variable lymphocyte receptors (VLRs) are the antigen receptors of jawless vertebrates such as lamprey. VLRs are of growing biotechnological interest for their ability to bind certain antigenic targets with higher...
3.
Tamhankar S, Shusta E, Palecek S
Cell Stem Cell
. 2025 Jan;
32(1):1-3.
PMID: 39753109
Tissue-engineered vascular conduits (TEVCs) are a promising blood vessel replacement. In a recent publication in Cell Stem Cell, Park et al. developed TEVCs comprised of decellularized human umbilical arteries lined...
4.
Boutom S, Silva T, Palecek S, Shusta E, Fernandes T, Ashton R
Cell Rep
. 2024 Dec;
43(12):115068.
PMID: 39693224
In recent years, neural organoids derived from human pluripotent stem cells (hPSCs) have offered a transformative pre-clinical platform for understanding central nervous system (CNS) development, disease, drug effects, and toxicology....
5.
Appelt E, Thoden J, Gehrke S, Bachmeier H, Rayment I, Shusta E, et al.
Proteins
. 2024 Nov;
93(4):801-811.
PMID: 39601379
Variable lymphocyte receptors (VLRs) are antigen receptors derived from the adaptive immune system of jawless vertebrates such as lamprey ( Petromyzon marinus ). First discovered in 2004, VLRs have been...
6.
Ding Y, Palecek S, Shusta E
Fluids Barriers CNS
. 2024 Oct;
21(1):79.
PMID: 39394110
Background: Three common isoforms of the apolipoprotein E (APOE) gene - APOE2, APOE3, and APOE4 - hold varying significance in Alzheimer's Disease (AD) risk. The APOE4 allele is the strongest...
7.
McCloskey M, Ahmad S, Widom L, Kasap P, Gastfriend B, Shusta E, et al.
Biomater Res
. 2024 Oct;
28():0081.
PMID: 39363889
Sepsis is the most lethal and expensive condition treated in intensive care units. Sepsis survivors frequently suffer long-term cognitive impairment, which has been linked to the breakdown of the blood-brain...
8.
Lopez-Morales J, Vanella R, Appelt E, Whillock S, Paulk A, Shusta E, et al.
Small Sci
. 2024 Jul;
3(12).
PMID: 39071103
Yeast surface display (YSD) is a powerful tool in biotechnology that links genotype to phenotype. In this review, the latest advancements in protein engineering and high-throughput screening based on YSD...
9.
Gastfriend B, Snyder M, Holt H, Daneman R, Palecek S, Shusta E
Sci Adv
. 2024 Feb;
10(5):eadi1737.
PMID: 38306433
Brain mural cells regulate development and function of the blood-brain barrier and control blood flow. Existing in vitro models of human brain mural cells have low expression of key mural...
10.
Choi E, Shusta E
Expert Opin Drug Deliv
. 2023 Nov;
20(12):1789-1800.
PMID: 38007619
Introduction: Numerous therapeutics for neurological diseases have been developed, but many have failed in clinical trials in part due to limited brain bioavailability, mainly stemming from inefficient transport through the...