Yong Ku Cho
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Explore the profile of Yong Ku Cho including associated specialties, affiliations and a list of published articles.
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26
Citations
1837
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Recent Articles
1.
Arbaciauskaite M, Pirhanov A, Paoloni J, Lei Y, Cho Y
STAR Protoc
. 2024 Aug;
5(3):103241.
PMID: 39093705
Developing antibodies with high specificity against post-translationally modified epitopes remains a challenge. Yeast biopanning is well suited in screening for high-specificity binders. Here, we present a protocol for screening and...
2.
Arbaciauskaite M, Pirhanov A, Ammermann E, Lei Y, Cho Y
Protein Eng Des Sel
. 2023 Jun;
36.
PMID: 37294629
The detection of site-specific phosphorylation in the microtubule-associated protein tau is emerging as a means to diagnose and monitor the progression of Alzheimer's Disease and other neurodegenerative diseases. However, there...
3.
Guo C, Jiang S, Yang L, Song P, Pirhanov A, Wang R, et al.
Biosens Bioelectron
. 2023 Jan;
224:115049.
PMID: 36623342
Imaging a large number of bio-specimens at high speed is essential for many biomedical applications. The common strategy is to place specimens at different lateral positions and image them sequentially....
4.
Mahrou B, Pirhanov A, Hadi Alijanvand M, Cho Y, Shin Y
Biosystems
. 2022 Jun;
219:104717.
PMID: 35690291
Generating robust, predictable perturbations in cellular protein levels will advance our understanding of protein function and enable the control of physiological outcomes in biotechnology applications. Timed periodic changes in protein...
5.
Arbaciauskaite M, Lei Y, Cho Y
Antib Ther
. 2021 Apr;
4(1):34-44.
PMID: 33928234
The ability to measure total and phosphorylated tau levels in clinical samples is transforming the detection of Alzheimer's disease (AD) and other neurodegenerative diseases. In particular, recent reports indicate that...
6.
Pirhanov A, Bridges C, Goodwin R, Guo Y, Furrer J, Shor L, et al.
ACS Synth Biol
. 2021 Jan;
10(2):345-356.
PMID: 33465305
Microorganisms play a vital role in shaping the soil environment and enhancing plant growth by interacting with plant root systems. Because of the vast diversity of cell types involved, combined...
7.
Lajoie J, Cho Y, Frost D, Bremner S, Li L, Shusta E
Protein Eng Des Sel
. 2019 Nov;
32(5):219-230.
PMID: 31769480
Yeast display immunoprecipitation is a combinatorial library screening platform for the discovery and engineering of antibodies against membrane proteins using detergent-solubilized membrane fractions or cell lysates as antigen sources. Here,...
8.
Wang S, Cho Y
Biotechnol Prog
. 2019 Oct;
36(1):e2920.
PMID: 31581367
Microtubule-associated protein tau is an intrinsically disordered, highly soluble protein found primarily in neurons. Under normal conditions, tau regulates the stability of axonal microtubules and intracellular vesicle transport. However, in...
9.
Li D, Cho Y
J Neurochem
. 2019 Jul;
152(1):122-135.
PMID: 31325178
Antibodies raised against defined phosphorylation sites of the microtubule-associated protein tau are widely used in scientific research and being applied in clinical assays. However, recent studies have revealed an alarming...
10.
Cho Y, Park D, Yang A, Chen F, Chuong A, Klapoetke N, et al.
J Biol Chem
. 2019 Jan;
294(11):3806-3821.
PMID: 30610117
Channelrhodopsins (ChRs) are light-gated ion channels in widespread use in neuroscience for mediating the genetically targetable optical control of neurons (optogenetics). ChRs pass multiple kinds of ions, and although nonspecific...