Koji L Foreman
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Explore the profile of Koji L Foreman including associated specialties, affiliations and a list of published articles.
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7
Citations
179
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Recent Articles
1.
Foreman K, Gastfriend B, Katt M, Palecek S, Shusta E
Biomolecules
. 2025 Feb;
15(2).
PMID: 40001496
Endothelial cells throughout the body sense blood flow, eliciting transcriptional and phenotypic responses. The brain endothelium, known as the blood-brain barrier (BBB), possesses unique barrier and transport properties, which are...
2.
Rivett E, Addis H, Dietz J, Carroll-Deaton J, Gupta S, Foreman K, et al.
Arch Biochem Biophys
. 2023 Jun;
744:109665.
PMID: 37348627
In eukaryotes and many aerobic prokaryotes, the final step of aerobic respiration is catalyzed by an aa-type cytochrome c oxidase, which requires a modified heme cofactor, heme a. The conversion...
3.
Foreman K, Shusta E, Palecek S
Methods Mol Biol
. 2023 Jun;
2683:113-133.
PMID: 37300771
The blood-brain barrier (BBB) comprises brain microvascular endothelial cells (BMECs) that form a high-resistance cellular interface that separates the blood compartment from the brain parenchyma. An intact BBB is pivotal...
4.
Gastfriend B, Nishihara H, Canfield S, Foreman K, Engelhardt B, Palecek S, et al.
Elife
. 2021 Nov;
10.
PMID: 34755601
Endothelial cells (ECs) in the central nervous system (CNS) acquire their specialized blood-brain barrier (BBB) properties in response to extrinsic signals, with Wnt/β-catenin signaling coordinating multiple aspects of this process....
5.
Gastfriend B, Foreman K, Katt M, Palecek S, Shusta E
J Cereb Blood Flow Metab
. 2021 May;
41(11):3052-3068.
PMID: 34027687
Brain mural cells, including pericytes and vascular smooth muscle cells, are important for vascular development, blood-brain barrier function, and neurovascular coupling, but the molecular characteristics of human brain mural cells...
6.
Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes
Pulido R, Munji R, Chan T, Quirk C, Weiner G, Weger B, et al.
Neuron
. 2020 Sep;
108(5):937-952.e7.
PMID: 32979312
The blood vessels in the central nervous system (CNS) have a series of unique properties, termed the blood-brain barrier (BBB), which stringently regulate the entry of molecules into the brain,...
7.
Song H, Foreman K, Gastfriend B, Kuo J, Palecek S, Shusta E
Sci Rep
. 2020 Jul;
10(1):12358.
PMID: 32704093
The brain vasculature maintains brain homeostasis by tightly regulating ionic, molecular, and cellular transport between the blood and the brain parenchyma. These blood-brain barrier (BBB) properties are impediments to brain...
8.
Floy M, Mateyka T, Foreman K, Palecek S
Stem Cell Res
. 2020 May;
45:101831.
PMID: 32446219
Coronary heart disease is one of the leading causes of death in the United States. Recent advances in stem cell biology have led to the development and engineering of human...