Eric Sterner
Overview
Explore the profile of Eric Sterner including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
292
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0
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Recent Articles
1.
Palte R, Juan V, Gomez-Llorente Y, Bailly M, Chakravarthy K, Chen X, et al.
Commun Biol
. 2021 Nov;
4(1):1310.
PMID: 34782734
No abstract available.
2.
Palte R, Juan V, Gomez-Llorente Y, Bailly M, Chakravarthy K, Chen X, et al.
Commun Biol
. 2021 Jul;
4(1):927.
PMID: 34326456
Human Arginase 1 (hArg1) is a metalloenzyme that catalyzes the hydrolysis of L-arginine to L-ornithine and urea, and modulates T-cell-mediated immune response. Arginase-targeted therapies have been pursued across several disease...
3.
Nanno Y, Sterner E, Gildersleeve J, Hering B, Burlak C
PLoS One
. 2021 Jun;
16(6):e0253029.
PMID: 34138941
Understanding the anti-carbohydrate antibody response toward epitopes expressed on porcine cells, tissues, and organs is critical to advancing xenotransplantation toward clinical application. In this study, we determined IgM and IgG...
4.
Nanno Y, Sterner E, Gildersleeve J, Hering B, Burlak C
Xenotransplantation
. 2019 Nov;
27(2):e12567.
PMID: 31762117
Background: Engineering of α-Galactosyltransferase gene-knockout pigs circumvented hyperacute rejection of pig organs after xenotransplantation in non-human primates. Overcoming this hurdle revealed the importance of non-α-Gal carbohydrate antigens in the immunobiology...
5.
Sterner E, Peach M, Nicklaus M, Gildersleeve J
Cell Rep
. 2017 Aug;
20(7):1681-1691.
PMID: 28813678
Antibodies play a crucial role in host defense and are indispensable research tools, diagnostics, and therapeutics. Antibody generation involves binding of genomically encoded germline antibodies followed by somatic hypermutation and...
6.
Ulaganathan T, Shi R, Yao D, Gu R, Garron M, Cherney M, et al.
Glycobiology
. 2016 Sep;
27(2):176-187.
PMID: 27621378
Glycosaminoglycans (GAGs) are linear polysaccharides comprised of disaccharide repeat units, a hexuronic acid, glucuronic acid or iduronic acid, linked to a hexosamine, N-acetylglucosamine (GlcNAc) or N-acetylgalactosamine. GAGs undergo further modification...
7.
Sterner E, Flanagan N, Gildersleeve J
ACS Chem Biol
. 2016 May;
11(7):1773-83.
PMID: 27220698
Antibodies are used extensively for a wide range of basic research and clinical applications. While an abundant and diverse collection of antibodies to protein antigens have been developed, good monoclonal...
8.
Sterner E, Masuko S, Li G, Li L, Green D, Otto N, et al.
J Biol Chem
. 2014 Feb;
289(14):9754-65.
PMID: 24563485
Four well-defined heparan sulfate (HS) block copolymers containing S-domains (high sulfo group content) placed adjacent to N-domains (low sulfo group content) were chemoenzymatically synthesized and characterized. The domain lengths in...
9.
Sterner E, Meli L, Kwon S, Dordick J, Linhardt R
Biochemistry
. 2013 Dec;
52(50):9009-19.
PMID: 24289246
Fibroblast growth factor (FGF) signals cell growth through its interaction with a fibroblast growth factor receptor (FGFR) and a glycosaminoglycn (GAG) coreceptor. Here, we examine the signaling of five different...
10.
Sterner E, Li L, Paul P, Beaudet J, Liu J, Linhardt R, et al.
Anal Bioanal Chem
. 2013 Nov;
406(2):525-36.
PMID: 24271188
O-sulfotransferases (OSTs) are critical enzymes in the cellular biosynthesis of the biologically and pharmacologically important heparan sulfate and heparin. Recently, these enzymes have been cloned and expressed in bacteria for...