Eric P Rahrmann
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Explore the profile of Eric P Rahrmann including associated specialties, affiliations and a list of published articles.
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24
Citations
868
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Recent Articles
11.
Rahrmann E, Wolf N, Otto G, Heltemes-Harris L, Ramsey L, Shu J, et al.
Mol Cancer Res
. 2018 Oct;
17(2):567-582.
PMID: 30355676
Follicular lymphoma and diffuse large B-cell lymphoma (DLBCL) are the most common non-Hodgkin lymphomas distinguishable by unique mutations, chromosomal rearrangements, and gene expression patterns. Here, it is demonstrated that early...
12.
Moriarity B, Otto G, Rahrmann E, Rathe S, Wolf N, Weg M, et al.
Nat Genet
. 2015 May;
47(6):615-24.
PMID: 25961939
Osteosarcomas are sarcomas of the bone, derived from osteoblasts or their precursors, with a high propensity to metastasize. Osteosarcoma is associated with massive genomic instability, making it problematic to identify...
13.
Rathe S, Moriarity B, Stoltenberg C, Kurata M, Aumann N, Rahrmann E, et al.
Sci Rep
. 2014 Aug;
4:6048.
PMID: 25116387
The evolution from microarrays to transcriptome deep-sequencing (RNA-seq) and from RNA interference to gene knockouts using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) and Transcription Activator-Like Effector Nucleases (TALENs) has...
14.
Rahrmann E, Moriarity B, Otto G, Watson A, Choi K, Collins M, et al.
Am J Pathol
. 2014 May;
184(7):2082-98.
PMID: 24832557
Malignant peripheral nerve sheath tumors (MPNSTs) are genetically diverse, aggressive sarcomas that occur sporadically or in association with neurofibromatosis type 1 syndrome. Reduced TP53 gene expression and amplification/overexpression of the...
15.
Moriarity B, Rahrmann E, Beckmann D, Conboy C, Watson A, Carlson D, et al.
PLoS One
. 2014 May;
9(5):e96114.
PMID: 24798371
The advent of Transcription Activator-Like Effector Nucleases (TALENs), and similar technologies such as CRISPR, provide a straightforward and cost effective option for targeted gene knockout (KO). Yet, there is still...
16.
Watson A, Anderson L, Greeley A, Keng V, Rahrmann E, Halfond A, et al.
Oncotarget
. 2014 Apr;
5(6):1502-14.
PMID: 24681606
Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that occur spontaneously, or from benign plexiform neurofibromas, in the context of the genetic disorder Neurofibromatosis Type 1 (NF1). The...
17.
Rahrmann E, Watson A, Keng V, Choi K, Moriarity B, Beckmann D, et al.
Nat Genet
. 2013 May;
45(7):756-66.
PMID: 23685747
Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas of Schwann cell lineage origin that occur sporadically or in association with the inherited syndrome neurofibromatosis type 1. To identify genetic drivers...
18.
19.
Watson A, Rahrmann E, Moriarity B, Choi K, Conboy C, Greeley A, et al.
Cancer Discov
. 2013 Mar;
3(6):674-89.
PMID: 23535903
Genetic changes required for the formation and progression of human Schwann cell tumors remain elusive. Using a Sleeping Beauty forward genetic screen, we identified several genes involved in canonical Wnt...
20.
Moriarity B, Rahrmann E, Keng V, Manlove L, Beckmann D, Wolf N, et al.
Nucleic Acids Res
. 2013 Feb;
41(8):e92.
PMID: 23444141
Studying complex biological processes such as cancer development, stem cell induction and transdifferentiation requires the modulation of multiple genes or pathways at one time in a single cell. Herein, we...