Christopher L Moertel
Overview
Explore the profile of Christopher L Moertel including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
570
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0
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Recent Articles
1.
Lamoureux A, Fisher M, Lemelle L, Pfaff E, Amir-Yazdani P, Kramm C, et al.
Clin Cancer Res
. 2024 Dec;
31(3):561-572.
PMID: 39625867
Purpose: Tropomyosin receptor kinase (TRK) fusions are detected in less than 2% of central nervous system tumors. There are limited data on the clinical course of affected patients. Experimental Design:...
2.
Moertel C, Hirbe A, Shuhaiber H, Bielamowicz K, Sidhu A, Viskochil D, et al.
J Clin Oncol
. 2024 Nov;
43(6):716-729.
PMID: 39514826
Purpose: Pharmacologic therapies for neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PNs) are limited; currently, none are US Food and Drug Administration-approved for adults. Methods: ReNeu is an open-label, multicenter, pivotal, phase...
3.
Raphael I, Mujeeb A, Ampudia-Mesias E, Sever R, McClellan B, Frederico S, et al.
bioRxiv
. 2024 Sep;
PMID: 39314283
Statement Of Significance: We demonstrate mechanisms of the druggable glioma-derived CD200 checkpoint on tumor growth and immune suppression.
4.
Ampudia-Mesias E, Cameron C, Yoo E, Kelly M, Anderson S, Manning R, et al.
Int J Mol Sci
. 2024 Apr;
25(8).
PMID: 38674001
Medulloblastoma (MB) encompasses diverse subgroups, and leptomeningeal disease/metastasis (LMD) plays a substantial role in associated fatalities. Despite extensive exploration of canonical genes in MB, the molecular mechanisms underlying LMD and...
5.
Williams K, Larsson A, Keller B, Chaney K, Williams R, Bhunia M, et al.
bioRxiv
. 2024 Apr;
PMID: 38585724
Neurofibromatosis Type 1 (NF1) is a common cancer predisposition syndrome, caused by heterozygous loss of function mutations in the tumor suppressor gene . Individuals with NF1 develop benign tumors of...
6.
Williams K, Marley A, Tibbitts J, Moertel C, Johnson K, Linden M, et al.
BMC Res Notes
. 2023 Oct;
16(1):275.
PMID: 37848948
Objective: In epidemiological and experimental research, high folic acid intake has been demonstrated to accelerate tumor development among populations with genetic and/or molecular susceptibility to cancer. Neurofibromatosis type 1 (NF1)...
7.
Moss R, Sorajja N, Mills L, Moertel C, Hoang T, Spector L, et al.
Front Oncol
. 2023 Apr;
13:1113121.
PMID: 37035203
Background: Medulloblastoma, the most common malignant pediatric brain tumor, displays marked sex differences in prevalence of the four main molecular subgroups: SHH, WNT, Group 3 and Group 4. Males are...
8.
Galvin R, Zheng C, Fitzpatrick G, Forster C, Sandoval-Garcia C, Guillaume D, et al.
Neurooncol Adv
. 2023 Apr;
5(1):vdad017.
PMID: 37025756
No abstract available.
9.
Domingues A, Moertel C, Marcotte E
Cancer Epidemiol Biomarkers Prev
. 2022 Apr;
31(9):1830-1838.
PMID: 35437584
Background: Recent investigations of malignant peripheral nerve sheath tumor (MPNST) survival have reported higher mortality among non-White individuals. However, previous analyses have not examined the impact of socioeconomic status (SES)...
10.
Moore K, Moertel C, Williams L
Cancer
. 2022 Feb;
128(8):1616-1625.
PMID: 35132626
Background: Central nervous system (CNS) tumors rank among the top 5 cancers diagnosed in young adults aged 20 to 39 years at diagnosis and show a clear male excess in...