Eric M Mendenhall
Overview
Explore the profile of Eric M Mendenhall including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
28
Citations
2606
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Partridge E, Chhetri S, Prokop J, Ramaker R, Jansen C, Goh S, et al.
Nature
. 2020 Jul;
583(7818):720-728.
PMID: 32728244
Transcription factors are DNA-binding proteins that have key roles in gene regulation. Genome-wide occupancy maps of transcriptional regulators are important for understanding gene regulation and its effects on diverse biological...
12.
Meadows S, Brandsmeier L, Newberry K, Betti M, Nesmith A, Mackiewicz M, et al.
Methods Mol Biol
. 2020 Jan;
2117:3-34.
PMID: 31960370
Chromatin immunoprecipitation followed by next-generation DNA sequencing (ChIP-seq) has been used to identify transcription factor (TF) binding proteins throughout the genome. Unfortunately, this approach traditionally requires commercially available, ChIP-seq grade...
13.
Swahn H, Ebron J, Lamar K, Yin S, Kerschner J, Nandymazumdar M, et al.
J Cell Mol Med
. 2019 Sep;
23(11):7726-7740.
PMID: 31557407
E74-like factor 5 (ELF5) and ETS-homologous factor (EHF) are epithelial selective ETS family transcription factors (TFs) encoded by genes at chr11p13, a region associated with cystic fibrosis (CF) lung disease...
14.
Prokop J, Yeo N, Ottmann C, Chhetri S, Florus K, Ross E, et al.
J Am Soc Nephrol
. 2018 Feb;
29(5):1525-1535.
PMID: 29476007
Interpreting genetic variants is one of the greatest challenges impeding analysis of rapidly increasing volumes of genomic data from patients. For example, is an associated risk gene for CKD, yet...
15.
Coppola C, Ramaker R, Mendenhall E
Hum Mol Genet
. 2016 Jul;
25(R2):R190-R197.
PMID: 27402881
The study of gene regulation has rapidly advanced by leveraging next-generation sequencing to identify and characterize the cis and trans elements that are critical for defining cell identity. These advances...
16.
Partridge E, Watkins T, Mendenhall E
Bioessays
. 2016 Jun;
38(8):801-11.
PMID: 27311628
Genome-wide identification of transcription factor binding sites with the ChIP-seq method is an extremely important scientific endeavor - one that should ideally be performed for every transcription factor in as...
17.
Savic D, Partridge E, Newberry K, Smith S, Meadows S, Roberts B, et al.
Genome Res
. 2015 Sep;
25(10):1581-9.
PMID: 26355004
Chromatin immunoprecipitation followed by next-generation DNA sequencing (ChIP-seq) is a widely used technique for identifying transcription factor (TF) binding events throughout an entire genome. However, ChIP-seq is limited by the...
18.
Biagioli M, Ferrari F, Mendenhall E, Zhang Y, Erdin S, Vijayvargia R, et al.
Hum Mol Genet
. 2015 Jan;
24(9):2442-57.
PMID: 25574027
The CAG repeat expansion in the Huntington's disease gene HTT extends a polyglutamine tract in mutant huntingtin that enhances its ability to facilitate polycomb repressive complex 2 (PRC2). To gain...
19.
Attanasio C, Nord A, Zhu Y, Blow M, Biddie S, Mendenhall E, et al.
Genome Res
. 2014 Apr;
24(6):920-9.
PMID: 24752179
The SMARCA4 (also known as BRG1 in humans) chromatin remodeling factor is critical for establishing lineage-specific chromatin states during early mammalian development. However, the role of SMARCA4 in tissue-specific gene...
20.
Mendenhall E, Williamson K, Reyon D, Zou J, Ram O, Joung J, et al.
Nat Biotechnol
. 2013 Sep;
31(12):1133-6.
PMID: 24013198
Mammalian gene regulation is dependent on tissue-specific enhancers that can act across large distances to influence transcriptional activity. Mapping experiments have identified hundreds of thousands of putative enhancers whose functionality...