Jill E Moore
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Explore the profile of Jill E Moore including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Moore J, Pratt H, Fan K, Phalke N, Fisher J, Elhajjajy S, et al.
bioRxiv
. 2025 Jan;
PMID: 39763870
Mammalian genomes contain millions of regulatory elements that control the complex patterns of gene expression. Previously, The ENCODE consortium mapped biochemical signals across many cell types and tissues and integrated...
2.
Kim A, Zhang Z, Legros C, Lu Z, de Smith A, Moore J, et al.
medRxiv
. 2024 May;
PMID: 38798383
The heritability of human diseases is extremely enriched in candidate regulatory elements (cRE) from disease-relevant cell types. Critical next steps are to infer which and how many cell types are...
3.
Yao D, Tycko J, Oh J, Bounds L, Gosai S, Lataniotis L, et al.
Nat Methods
. 2024 Mar;
21(4):723-734.
PMID: 38504114
The ENCODE Consortium's efforts to annotate noncoding cis-regulatory elements (CREs) have advanced our understanding of gene regulatory landscapes. Pooled, noncoding CRISPR screens offer a systematic approach to investigate cis-regulatory mechanisms....
4.
Schmid T, Elie J, Redlich R, Shvareva V, Rakuljic A, Ji M, et al.
Science
. 2024 Feb;
383(6690):eabn3263.
PMID: 38422184
Vocal production learning ("vocal learning") is a convergently evolved trait in vertebrates. To identify brain genomic elements associated with mammalian vocal learning, we integrated genomic, anatomical, and neurophysiological data from...
5.
Gschwind A, Mualim K, Karbalayghareh A, Sheth M, Dey K, Jagoda E, et al.
bioRxiv
. 2023 Nov;
PMID: 38014075
Identifying transcriptional enhancers and their target genes is essential for understanding gene regulation and the impact of human genetic variation on disease. Here we create and evaluate a resource of...
6.
Reese F, Williams B, Balderrama-Gutierrez G, Wyman D, Celik M, Rebboah E, et al.
bioRxiv
. 2023 Jun;
PMID: 37292896
The majority of mammalian genes encode multiple transcript isoforms that result from differential promoter use, changes in exonic splicing, and alternative 3' end choice. Detecting and quantifying transcript isoforms across...
7.
Andrews G, Fan K, Pratt H, Phalke N, Karlsson E, Lindblad-Toh K, et al.
Science
. 2023 Apr;
380(6643):eabn7930.
PMID: 37104580
Understanding the regulatory landscape of the human genome is a long-standing objective of modern biology. Using the reference-free alignment across 241 mammalian genomes produced by the Zoonomia Consortium, we charted...
8.
Rozowsky J, Gao J, Borsari B, Yang Y, Galeev T, Gursoy G, et al.
Cell
. 2023 Mar;
186(7):1493-1511.e40.
PMID: 37001506
Understanding how genetic variants impact molecular phenotypes is a key goal of functional genomics, currently hindered by reliance on a single haploid reference genome. Here, we present the EN-TEx resource...
9.
Xu J, Pratt H, Moore J, Gerstein M, Weng Z
Hum Mol Genet
. 2022 Sep;
31(R1):R114-R122.
PMID: 36083269
Every cell in the human body inherits a copy of the same genetic information. The three billion base pairs of DNA in the human genome, and the roughly 50 000...
10.
Snyder M, Gingeras T, Moore J, Weng Z, Gerstein M, Ren B, et al.
Nature
. 2022 Apr;
605(7909):E4.
PMID: 35474002
No abstract available.