Eric M Mendenhall
Overview
Explore the profile of Eric M Mendenhall including associated specialties, affiliations and a list of published articles.
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28
Citations
2606
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Recent Articles
1.
Patel L, Cao Y, Mendenhall E, Benner C, Goren A
Nat Biotechnol
. 2024 Sep;
42(9):1343-1349.
PMID: 39271835
No abstract available.
2.
Anderson A, Moyers B, Loupe J, Rodriguez-Nunez I, Felker S, Lawlor J, et al.
Genome Res
. 2024 Aug;
34(8):1224-1234.
PMID: 39152038
Transcription factors (TFs) regulate gene expression by facilitating or disrupting the formation of transcription initiation machinery at particular genomic loci. Because TF occupancy is driven in part by recognition of...
3.
Moyers B, Loupe J, Felker S, Lawlor J, Anderson A, Rodriguez-Nunez I, et al.
bioRxiv
. 2023 Oct;
PMID: 37873117
Transcription Factors (TFs) influence gene expression by facilitating or disrupting the formation of transcription initiation machinery at particular genomic loci. Because genomic localization of TFs is in part driven by...
4.
Moyers B, Partridge E, Mackiewicz M, Betti M, Darji R, Meadows S, et al.
Genome Res
. 2023 Oct;
33(11):1879-1892.
PMID: 37852782
Transcription factors (TFs) are -acting proteins that bind -regulatory elements (CREs) in DNA to control gene expression. Here, we analyzed the genomic localization profiles of 529 sequence-specific TFs and 151...
5.
Rozowsky J, Gao J, Borsari B, Yang Y, Galeev T, Gursoy G, et al.
Cell
. 2023 Mar;
186(7):1493-1511.e40.
PMID: 37001506
Understanding how genetic variants impact molecular phenotypes is a key goal of functional genomics, currently hindered by reliance on a single haploid reference genome. Here, we present the EN-TEx resource...
6.
Snyder M, Gingeras T, Moore J, Weng Z, Gerstein M, Ren B, et al.
Nature
. 2022 Apr;
605(7909):E4.
PMID: 35474002
No abstract available.
7.
Moore J, Purcaro M, Pratt H, Epstein C, Shoresh N, Adrian J, et al.
Nature
. 2022 Apr;
605(7909):E3.
PMID: 35474001
No abstract available.
8.
A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion
Sharma J, Du M, Wong E, Mutyam V, Li Y, Chen J, et al.
Nat Commun
. 2021 Jul;
12(1):4358.
PMID: 34272367
Premature termination codons (PTCs) prevent translation of a full-length protein and trigger nonsense-mediated mRNA decay (NMD). Nonsense suppression (also termed readthrough) therapy restores protein function by selectively suppressing translation termination...
9.
Moore J, Purcaro M, Pratt H, Epstein C, Shoresh N, Adrian J, et al.
Nature
. 2020 Jul;
583(7818):699-710.
PMID: 32728249
The human and mouse genomes contain instructions that specify RNAs and proteins and govern the timing, magnitude, and cellular context of their production. To better delineate these elements, phase III...
10.
Snyder M, Gingeras T, Moore J, Weng Z, Gerstein M, Ren B, et al.
Nature
. 2020 Jul;
583(7818):693-698.
PMID: 32728248
The Encylopedia of DNA Elements (ENCODE) Project launched in 2003 with the long-term goal of developing a comprehensive map of functional elements in the human genome. These included genes, biochemical...