Bret H Goodpaster
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Explore the profile of Bret H Goodpaster including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Yeo R, Mau T, Ross Z, Edenhoffer N, Liu J, Barnes H, et al.
J Gerontol A Biol Sci Med Sci
. 2025 Jan;
PMID: 39886989
Background: Age-related changes in adipose tissue impact chronic medical diseases and mobility disability but mechanism remains poorly understood. The goal of this study is to define methods for phenotyping unique...
2.
Yu Q, Zhang Z, Herold F, Ludyga S, Kuang J, Chen Y, et al.
Trends Mol Med
. 2025 Jan;
PMID: 39848868
Regular physical activity (PA) is beneficial for cognitive health, and cathepsin B (CTSB) - a protease released by skeletal muscle during PA - acts as a potential molecular mediator of...
3.
Horowitz J, Goodpaster B
Diabetes
. 2025 Jan;
74(2):134-137.
PMID: 39836884
Endurance exercise is widely recognized for its role in mitigating insulin resistance, yet the precise mechanisms remain unclear. In this Classics in Diabetes article, we revisit the article by Amati...
4.
Vieira F, Cai Y, Gonzalez M, Goodpaster B, Prado C, Haqq A
Rev Endocr Metab Disord
. 2025 Jan;
PMID: 39833502
Poor muscle quality (MQ) is a hidden health condition in obesity, commonly disregarded and underdiagnosed, associated with poor health-related outcomes. This narrative review provides an in-depth exploration of MQ in...
5.
Mau T, Blackwell T, Cawthon P, Molina A, Coen P, Distefano G, et al.
medRxiv
. 2024 Dec;
PMID: 39711735
Background: The geroscience hypothesis posits that aging biological processes contribute to many age-related deficits, including the accumulation of multiple chronic diseases. Though only one facet of mitochondrial function, declines in...
6.
Mau T, Barnes H, Simon C, Hetherington-Rauth M, Bauer S, Strotmeyer E, et al.
medRxiv
. 2024 Dec;
PMID: 39711718
Background: Musculoskeletal pain frequently accompanies the development of mobility disability and falls in old age. To better understand this, we aimed to quantify the impact of different pain measures-recalled pain...
7.
Gay E, Coen P, Harrison S, Garcia R, Qiao Y, Goodpaster B, et al.
Geroscience
. 2024 Oct;
PMID: 39436549
Greater perceived physical fatigability and lower skeletal muscle energetics are both predictors of mobility decline. Characterizing associations between muscle energetics and perceived fatigability may provide insight into potential targets to...
8.
Serrano J, Kondo S, Link G, Brown I, Pratley R, Baskin K, et al.
Metabolism
. 2024 Oct;
162:156045.
PMID: 39393515
Background: The TAS1R2 receptor, known for its role in taste perception, has also emerged as a key regulator of muscle physiology. Previous studies have shown that genetic ablation of TAS1R2...
9.
Mucinski J, Distefano G, Dube J, Toledo F, Coen P, Goodpaster B, et al.
J Clin Endocrinol Metab
. 2024 Aug;
PMID: 39207205
Objectives: Non-Hispanic black women (BW) have a greater risk of type 2 diabetes (T2D) and insulin resistance (IR) compared to non-Hispanic white women (WW). The mechanisms leading to these differences...
10.
Doerrier C, Gama-Perez P, Pesta D, Distefano G, Soendergaard S, Chroeis K, et al.
Free Radic Biol Med
. 2024 Aug;
223:384-397.
PMID: 39097206
Aim: High-resolution respirometry in human permeabilized muscle fibers is extensively used for analysis of mitochondrial adaptions to nutrition and exercise interventions, and is linked to athletic performance. However, the lack...