Eoin N McNamee
Overview
Explore the profile of Eoin N McNamee including associated specialties, affiliations and a list of published articles.
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48
Citations
2120
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Recent Articles
11.
Masterson J, Biette K, Hammer J, Nguyen N, Capocelli K, Saeedi B, et al.
J Clin Invest
. 2019 Jul;
129(8):3224-3235.
PMID: 31264974
Epithelial barrier dysfunction is a significant factor in many allergic diseases, including eosinophilic esophagitis (EoE). Infiltrating leukocytes and tissue adaptations increase metabolic demands and decrease oxygen availability at barrier surfaces....
12.
Jones J, Brindley C, Elder N, Myers Jr M, Rajala M, Dekaney C, et al.
Cell Mol Gastroenterol Hepatol
. 2019 Mar;
7(3):533-554.
PMID: 30827941
Background & Aims: Loss of leucine-rich repeat-containing G-protein-coupled receptor 5-positive crypt base columnar cells provides permissive conditions for different facultative stem cell populations to dedifferentiate and repopulate the stem cell...
13.
McNamee E
J Clin Invest
. 2019 Jan;
129(2):499-502.
PMID: 30640177
A predominant feature of intestinal inflammation is the accumulation of neutrophils, which dictates a fine balance between epithelial repair or progression to chronic inflammation. While the processes of mucosal healing...
14.
Grenz A, Bauerle J, Dalton J, Ridyard D, Badulak A, Tak E, et al.
J Clin Invest
. 2017 Jun;
127(6):2438.
PMID: 28569735
No abstract available.
15.
Neudecker V, Haneklaus M, Jensen O, Khailova L, Masterson J, Tye H, et al.
J Exp Med
. 2017 May;
214(6):1737-1752.
PMID: 28487310
MicroRNA (miRNA)-mediated RNA interference regulates many immune processes, but how miRNA circuits orchestrate aberrant intestinal inflammation during inflammatory bowel disease (IBD) is poorly defined. Here, we report that miR-223 limits...
16.
McNamee E, Rivera-Nieves J
Gastroenterology
. 2017 Feb;
152(4):908-910.
PMID: 28153586
No abstract available.
17.
Hoegl S, Ehrentraut H, Brodsky K, Victorino F, Golden-Mason L, Eltzschig H, et al.
J Leukoc Biol
. 2016 Sep;
101(2):471-480.
PMID: 27601626
A critical step in the pathogenesis of acute lung injury (ALI) is excessive recruitment of polymorphonuclear neutrophils (PMNs) into the lungs, causing significant collateral tissue damage. Defining the molecular and...
18.
McNamee E, Rivera-Nieves J
Front Immunol
. 2016 Sep;
7:308.
PMID: 27579025
Organized lymphoid tissues like the thymus first appeared in jawed vertebrates around 500 million years ago and have evolved to equip the host with a network of specialized sites, strategically...
19.
Frasch S, McNamee E, Kominsky D, Jedlicka P, Jakubzick C, Zemski Berry K, et al.
J Immunol
. 2016 Jul;
197(4):1425-34.
PMID: 27402702
Proinflammatory consequences have been described for lysophosphatidylcholine, a lipid product of cellular injury, signaling via the G protein-coupled receptor G2A on myeloid and lymphoid inflammatory cells. This prompted the hypothesis...
20.
McNamee E, Vohwinkel C, Eltzschig H
Sci Signal
. 2016 Jun;
9(430):fs11.
PMID: 27245611
In this issue of Science Signaling, Bullen et al demonstrate that protein kinase A (PKA) phosphorylates and stimulates the transcriptional activity of hypoxia-inducible transcription factor-1α (HIF-1α). This finding may have...