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Emily A Todd

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Citations 86
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Recent Articles
1.
Dargam V, Sanchez A, Kolengaden A, Perez Y, Arias R, Valentin Cabrera A, et al.
J Cardiovasc Dev Dis . 2024 Nov; 11(11). PMID: 39590205
Chronic kidney disease (CKD) and cardiovascular disease (CVD) often co-exist, with notable sex-dependent differences in manifestation and progression despite both sexes sharing similar risk factors. Identifying sex-specific diagnostic markers in...
2.
Lv K, Jiang J, Donaghy R, Riling C, Cheng Y, Chandra V, et al.
Genes Dev . 2017 Jun; 31(10):1007-1023. PMID: 28611190
Janus kinase 2 (JAK2) is a central kinase in hematopoietic stem/progenitor cells (HSPCs), and its uncontrolled activation is a prominent oncogenic driver of hematopoietic neoplasms. However, molecular mechanisms underlying the...
3.
Padala P, Oweis W, Mashahreh B, Soudah N, Cohen-Kfir E, Todd E, et al.
Sci Rep . 2017 Apr; 7(1):508. PMID: 28360427
The modification of proteins by ubiquitin-fold modifier 1 (UFM1) is implicated in many human diseases. Prior to conjugation, UFM1 undergoes activation by its cognate activating enzyme, UBA5. UBA5 is a...
4.
Oweis W, Padala P, Hassouna F, Cohen-Kfir E, Gibbs D, Todd E, et al.
Cell Rep . 2016 Sep; 16(12):3113-3120. PMID: 27653677
Modification of proteins by ubiquitin or ubiquitin-like proteins (UBLs) is a critical cellular process implicated in a variety of cellular states and outcomes. A prerequisite for target protein modification by...
5.
Baiady N, Padala P, Mashahreh B, Cohen-Kfir E, Todd E, Du Pont K, et al.
J Biol Chem . 2015 Nov; 291(4):2033-2042. PMID: 26601948
The deubiquitinating enzyme associated molecule with the SH3 domain of STAM (AMSH) is crucial for the removal of ubiquitin molecules during receptor-mediated endocytosis and lysosomal receptor sorting. AMSH interacts with...
6.
Putney D, Todd E, Berndsen C, Wright N
Biomol NMR Assign . 2015 May; 9(2):407-10. PMID: 25947351
The ubiquitination pathway controls several human cellular processes, most notably protein degradation. Ubiquitin, a small signaling protein, is activated by the E1 activating enzyme, transferred to an E2 conjugating enzyme,...