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Einav Cohen-Kfir

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Articles 21
Citations 339
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Recent Articles
1.
Assayag E, Gurt I, Cohen-Kfir E, Stokar J, Zwas D, Dresner-Pollak R
Int J Mol Sci . 2024 May; 25(10). PMID: 38791190
Heart failure with preserved ejection fraction (HFpEF) is more prevalent in post- compared to pre-menopausal women. The underlying mechanisms are not fully understood. Data in humans is confounded by age...
2.
Banerjee S, Varga J, Kumar M, Zoltsman G, Rotem-Bamberger S, Cohen-Kfir E, et al.
EMBO Rep . 2023 Nov; 24(12):e56920. PMID: 37988244
Ufmylation plays a crucial role in various cellular processes including DNA damage response, protein translation, and ER homeostasis. To date, little is known about how the enzymes responsible for ufmylation...
3.
Stolovich-Rain M, Kumari S, Friedman A, Kirillov S, Socol Y, Billan M, et al.
Front Immunol . 2023 Feb; 13:933347. PMID: 36798518
Intramuscularly administered vaccines stimulate robust serum neutralizing antibodies, yet they are often less competent in eliciting sustainable "sterilizing immunity" at the mucosal level. Our study uncovers a strong temporary neutralizing...
4.
Artsi H, Cohen-Kfir E, Shahar R, Kalish-Achrai N, Lishinsky N, Dresner-Pollak R
Front Endocrinol (Lausanne) . 2022 Dec; 13:1032262. PMID: 36568088
Introduction: Sirtuin 1 (SIRT1) is a key player in aging and metabolism and regulates bone mass and architecture. Sexual dimorphism in skeletal effects of SIRT1 has been reported, with an...
5.
Kumari S, Banerjee S, Kumar M, Hayashi A, Solaimuthu B, Cohen-Kfir E, et al.
Int J Mol Sci . 2022 Jul; 23(13). PMID: 35806453
Ufmylation is a posttranslational modification in which the modifier UFM1 is attached to target proteins. This conjugation requires the concerted work of three enzymes named UBA5, UFC1, and UFL1. Initially,...
6.
Stokar J, Gurt I, Cohen-Kfir E, Yakubovsky O, Hallak N, Benyamini H, et al.
Mol Metab . 2022 Apr; 60:101482. PMID: 35364299
Objective: Menopause is associated with visceral adiposity, hepatic steatosis and increased risk for cardiovascular disease. As estrogen replacement therapy is not suitable for all postmenopausal women, a need for alternative...
7.
Kumar M, Padala P, Fahoum J, Hassouna F, Tsaban T, Zoltsman G, et al.
Nat Commun . 2021 Sep; 12(1):5708. PMID: 34588452
Ufmylation is a post-translational modification essential for regulating key cellular processes. A three-enzyme cascade involving E1, E2 and E3 is required for UFM1 attachment to target proteins. How UBA5 (E1)...
8.
Babkoff A, Cohen-Kfir E, Aharon H, Ravid S
J Biol Chem . 2021 Aug; 297(3):101024. PMID: 34343568
Cytokinesis, the final step of mitosis, is mediated by an actomyosin contractile ring, the formation of which is temporally and spatially regulated following anaphase onset. Aurora-B is a member of...
9.
Babkoff A, Cohen-Kfir E, Aharon H, Ronen D, Rosenberg M, Wiener R, et al.
J Cell Sci . 2019 Jul; 132(14). PMID: 31315909
An acto-myosin contractile ring, which forms after anaphase onset and is highly regulated in time and space, mediates cytokinesis, the final step of mitosis. The chromosomal passenger complex (CPC), composed...
10.
Artsi H, Gurt I, El-Haj M, Muller R, Kuhn G, Ben Shalom G, et al.
Front Endocrinol (Lausanne) . 2019 Mar; 10:126. PMID: 30873124
Bone marrow adipose tissue (MAT) is influenced by nutritional cues, and participates in whole body energy metabolism. To investigate the role of Sirtuin1 (Sirt1), a key player in metabolism, in...