Edward P Manning
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Explore the profile of Edward P Manning including associated specialties, affiliations and a list of published articles.
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27
Citations
375
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Recent Articles
1.
Ramachandra A, Sharma P, De Man R, Nikola F, Guerrera N, Doddaballapur P, et al.
bioRxiv
. 2025 Mar;
PMID: 40027757
Hypoxemia impairs cardiopulmonary function. We investigated pulmonary artery remodeling in mice exposed to chronic hypoxia for up to five weeks and quantified associated changes in cardiac and lung function, without...
2.
Manning E, Mishall P, Ramachandra A, Hassab A, Lamy J, Peters D, et al.
Physiol Rep
. 2024 Jun;
12(12):e16090.
PMID: 38884325
Adverse effects of large artery stiffening are well established in the systemic circulation; stiffening of the proximal pulmonary artery (PPA) and its sequelae are poorly understood. We combined in vivo...
3.
Ramachandra A, Jiang B, Jennings I, Manning E, Humphrey J
J Biomech Eng
. 2024 Feb;
146(8).
PMID: 38421341
Chronic hypoxia plays a central role in diverse pulmonary pathologies, but its effects on longitudinal changes in the biomechanical behavior of proximal pulmonary arteries remain poorly understood. Similarly, effects of...
4.
Barnthaler T, Ramachandra A, Ebanks S, Guerrera N, Sharma L, Dela Cruz C, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Feb;
326(5):L627-L637.
PMID: 38375577
Pulmonary function testing (PFT) in mice includes biomechanical assessment of lung function relevant to physiology in health and its alteration in disease, hence, it is frequently used in preclinical modeling...
5.
Weil K, Baumann V, Brown B, Nadeau R, Gerstenhaber B, Manning E
HSOA J Pulm Med Respir Res
. 2024 Jan;
9(1).
PMID: 38188724
Prolonged time on mechanical ventilation is associated with multiple consequences for both the patient and medical facility. Based on anecdotal evidence that sustained elevation of beta-natriuretic protein (BNP) during a...
6.
Schupp J, Manning E, Chioccioli M, Kamp J, Christian L, Ryu C, et al.
Am J Respir Crit Care Med
. 2023 Aug;
208(7):819-822.
PMID: 37552025
No abstract available.
7.
Weil K, Baumann V, Brown B, Nadeau R, Gerstenhaber B, Manning E
J Mech Vent
. 2023 Jul;
4(1):1-8.
PMID: 37426175
Purpose: Tracheostomy is a necessary procedure required for prolonged mechanical ventilation in long-term acute care hospitals (LTACH). Many factors influence successful decannulation, or tracheostomy removal, and it is unclear what...
8.
De Man R, McDonough J, Adams T, Manning E, Myers G, Vos R, et al.
bioRxiv
. 2023 May;
PMID: 37131739
Age is a major risk factor for lung disease. To understand the mechanisms underlying this association, we characterized the changing cellular, genomic, transcriptional, and epigenetic landscape of lung aging using...
9.
Harris Z, Sun Y, Joerns J, Clark B, Hu B, Korde A, et al.
Oxid Med Cell Longev
. 2022 Oct;
2022:9518592.
PMID: 36193076
Aims: Studies have linked severe hyperoxia, or prolonged exposure to very high oxygen levels, with worse clinical outcomes. This study investigated the role of epidermal growth factor receptor (EGFR) in...
10.
Ramachandra A, Mikush N, Sauler M, Humphrey J, Manning E
J Biomech Eng
. 2022 Feb;
144(8).
PMID: 35171214
Competent elastic fibers are critical to the function of the lung and right circulation. Murine models of elastopathies can aid in understanding the functional roles of the elastin and elastin-associated...