Abhay B Ramachandra
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Explore the profile of Abhay B Ramachandra including associated specialties, affiliations and a list of published articles.
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34
Citations
373
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Recent Articles
1.
Ramachandra A, Sharma P, De Man R, Nikola F, Guerrera N, Doddaballapur P, et al.
bioRxiv
. 2025 Mar;
PMID: 40027757
Hypoxemia impairs cardiopulmonary function. We investigated pulmonary artery remodeling in mice exposed to chronic hypoxia for up to five weeks and quantified associated changes in cardiac and lung function, without...
2.
Jiang B, Ren P, He C, Wang M, Murtada S, Ruiz-Rodriguez M, et al.
JCI Insight
. 2025 Feb;
PMID: 39932797
Hypertension and transient increases in blood pressure from extreme exertion are risk factors for aortic dissection in patients with age-related vascular degeneration or inherited connective tissue disorders. Yet, a common...
3.
Giudici A, Szafron J, Ramachandra A, Spronck B
Ann Biomed Eng
. 2024 Jul;
52(9):2403-2416.
PMID: 38949730
Purpose: Through their contractile and synthetic capacity, vascular smooth muscle cells (VSMCs) can regulate the stiffness and resistance of the circulation. To model the contraction of blood vessels, an active...
4.
Manning E, Mishall P, Ramachandra A, Hassab A, Lamy J, Peters D, et al.
Physiol Rep
. 2024 Jun;
12(12):e16090.
PMID: 38884325
Adverse effects of large artery stiffening are well established in the systemic circulation; stiffening of the proximal pulmonary artery (PPA) and its sequelae are poorly understood. We combined in vivo...
5.
Jiang B, Ren P, He C, Wang M, Murtada S, Chen Y, et al.
bioRxiv
. 2024 May;
PMID: 38712205
Hypertension and transient increases in blood pressure from extreme exertion are risk factors for aortic dissection in patients with age-related vascular degeneration or inherited connective tissue disorders. Yet, the common...
6.
Ramachandra A, Jiang B, Jennings I, Manning E, Humphrey J
J Biomech Eng
. 2024 Feb;
146(8).
PMID: 38421341
Chronic hypoxia plays a central role in diverse pulmonary pathologies, but its effects on longitudinal changes in the biomechanical behavior of proximal pulmonary arteries remain poorly understood. Similarly, effects of...
7.
Barnthaler T, Ramachandra A, Ebanks S, Guerrera N, Sharma L, Dela Cruz C, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Feb;
326(5):L627-L637.
PMID: 38375577
Pulmonary function testing (PFT) in mice includes biomechanical assessment of lung function relevant to physiology in health and its alteration in disease, hence, it is frequently used in preclinical modeling...
8.
Ramachandra A, Cavinato C, Humphrey J
Ann Biomed Eng
. 2024 Jan;
52(4):958-966.
PMID: 38227167
The greater thoracic vessels are central to a well-functioning circulatory system and are often targeted in congenital heart surgeries, yet the structure and function of these vessels have not been...
9.
Murtada S, Kawamura Y, Cavinato C, Wang M, Ramachandra A, Spronck B, et al.
Biomech Model Mechanobiol
. 2023 May;
22(4):1333-1347.
PMID: 37149823
Hutchinson-Gilford Progeria Syndrome results in rapid aging and severe cardiovascular sequelae that accelerate near end-of-life. We found a progressive disease process in proximal elastic arteries that was less evident in...
10.
Ban E, Kalogerakos P, Khosravi R, Ziganshin B, Ellauzi H, Ramachandra A, et al.
Int J Cardiovasc Imaging
. 2023 Apr;
39(7):1345-1356.
PMID: 37046157
The cross-sectional shape of the aortic root is cloverleaf, not circular, raising controversy regarding how best to measure its radiographic "diameter" for aortic event prediction. We mathematically extended the law...