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Naftali Kaminski

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Articles 378
Citations 19064
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Recent Articles
1.
Ramachandra A, Sharma P, De Man R, Nikola F, Guerrera N, Doddaballapur P, et al.
bioRxiv . 2025 Mar; PMID: 40027757
Hypoxemia impairs cardiopulmonary function. We investigated pulmonary artery remodeling in mice exposed to chronic hypoxia for up to five weeks and quantified associated changes in cardiac and lung function, without...
2.
Chin D, Hernandez-Beeftink T, Donoghue L, Guillen-Uio B, Guillen-Guio B, Leavy O, et al.
medRxiv . 2025 Feb; PMID: 39974050
Background: Idiopathic pulmonary fibrosis (IPF) is a rare, incurable lung disease with a median survival of 3-5 years after diagnosis. Treatment options are limited. Genetic association studies can identify new...
3.
Kurbanov D, Ahangari F, Adams T, De Man R, Tang J, Carlon M, et al.
Am J Physiol Lung Cell Mol Physiol . 2025 Feb; 328(3):L456-L462. PMID: 39970931
In this research, we delve into the association between epigenetic aging and idiopathic pulmonary fibrosis (IPF), a debilitating lung disease that progresses over time. Utilizing the Illumina MethylationEPIC array, we...
4.
Carter H, Costa R, Adams T, Gilchrist T, Emch C, Bame M, et al.
JCI Insight . 2025 Feb; PMID: 39964756
Idiopathic pulmonary fibrosis (IPF) is characterized by progressive scarring and loss of lung function. With limited treatment options, patients succumb to the disease within 2 to 5 years. The molecular...
5.
Yuan Y, Sharma L, Tang W, Yoon Y, Kirk S, Raredon M, et al.
bioRxiv . 2025 Jan; PMID: 39763730
Disorders in pulmonary vascular integrity are a prominent feature in many lung diseases. Paracrine signaling is highly enriched in the lung and plays a crucial role in regulating vascular homeostasis....
6.
Song Q, Singh A, McDonough J, Adams T, Vos R, De Man R, et al.
PLoS Comput Biol . 2024 Dec; 20(12):e1012632. PMID: 39700255
Age prediction based on single cell RNA-Sequencing data (scRNA-Seq) can provide information for patients' susceptibility to various diseases and conditions. In addition, such analysis can be used to identify aging...
7.
Sakamachi Y, Wiley E, Solis A, Johnson C, Meng X, Hussain S, et al.
bioRxiv . 2024 Nov; PMID: 39605370
One-sentence Summary: Deficiency in the innate immune receptor TLR5 is a risk factor for pulmonary fibrosis, because TLR5 prevents microbial dysbiosis after lung injury.
8.
Lehmann M, Krishnan R, Sucre J, Kulkarni H, Pineda R, Anderson C, et al.
Am J Respir Cell Mol Biol . 2024 Nov; PMID: 39499861
The urgent need for effective treatments for acute and chronic lung diseases underscores the significance of developing innovative preclinical human research tools. The 2023 ATS Workshop on Precision Cut Lung...
9.
Liu Y, Li N, Qi J, Xu G, Zhao J, Wang N, et al.
Genome Biol . 2024 Oct; 25(1):271. PMID: 39402626
Spatial barcoding-based transcriptomic (ST) data require deconvolution for cellular-level downstream analysis. Here we present SDePER, a hybrid machine learning and regression method to deconvolve ST data using reference single-cell RNA...
10.
Karampitsakos T, Tourki B, Jia M, Perrot C, Visinescu B, Zhao A, et al.
medRxiv . 2024 Aug; PMID: 39211854
Rationale: The association between immune-cell-specific transcriptomic profiles and Idiopathic Pulmonary Fibrosis (IPF) mortality is unknown. Objectives: To determine immune-cell-specific transcriptomic profiles associated with IPF mortality. Methods: We profiled peripheral blood...