Edward J Weinman
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Explore the profile of Edward J Weinman including associated specialties, affiliations and a list of published articles.
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75
Citations
1924
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Recent Articles
1.
Yang J, Asico L, Beitelshees A, Feranil J, Wang X, Jones J, et al.
FASEB J
. 2020 Apr;
34(6):7941-7957.
PMID: 32293069
Acute renal depletion of sorting nexin 1 (SNX1) in mice results in blunted natriuretic response and hypertension due to impaired dopamine D receptor (D R) activity. We elucidated the molecular...
2.
Pushpakumar S, Ahmad A, Ketchem C, Jose P, Weinman E, Sen U, et al.
Life Sci
. 2020 Jan;
243:117226.
PMID: 31904366
Hypertension is a risk factor for premature death and roughly 50% of hypertensive patients are salt-sensitive. The incidence of salt-sensitive hypertension increases with age. However, the mechanisms of salt-sensitive hypertension...
3.
Woodard L, Welch R, Veach R, Beckermann T, Sha F, Weinman E, et al.
BMC Nephrol
. 2019 Jun;
20(1):227.
PMID: 31221135
Background: Cystinuria is an inherited disorder of renal amino acid transport that causes recurrent nephrolithiasis and significant morbidity in humans. It has an incidence of 1 in 7000 worldwide making...
4.
Pera T, Tompkins E, Katz M, Wang B, Deshpande D, Weinman E, et al.
FASEB J
. 2019 May;
33(8):9008-9016.
PMID: 31042404
Na/H exchanger regulatory factor 1 (NHERF1; also known as ezrin-radixin-moesin-binding phosphoprotein 50) is a PSD-95, disc large, zona occludens-1 adapter that acts as a scaffold for signaling complexes and cytoskeletal-plasma...
5.
Barati M, Ketchem C, Merchant M, Kusiak W, Jose P, Weinman E, et al.
Am J Physiol Cell Physiol
. 2017 May;
313(2):C197-C206.
PMID: 28515088
Dopamine decreases Na-K-ATPase (NKA) activity by PKC-dependent phosphorylation and endocytosis of the NKA α1. Dopamine-mediated regulation of NKA is impaired in aging and some forms of hypertension. Using opossum (OK)...
6.
Ritter-Makinson S, Paquet M, Bogenpohl J, Rodin R, Yun C, Weinman E, et al.
Neuroscience
. 2017 Apr;
353:58-75.
PMID: 28392297
The group II metabotropic glutamate receptors mGluR2 and mGluR3 are key modulators of glutamatergic neurotransmission. In order to identify novel Group II metabotropic glutamate receptor (mGluR)-interacting partners, we screened the...
7.
He P, Zhao L, Zhu L, Weinman E, De Giorgio R, Koval M, et al.
J Clin Invest
. 2015 Aug;
125(9):3519-31.
PMID: 26258413
Diarrhea is one of the troublesome complications of diabetes, and the underlying causes of this problem are complex. Here, we investigated whether altered electrolyte transport contributes to diabetic diarrhea. We...
8.
Li M, Mennone A, Soroka C, Hagey L, Ouyang X, Weinman E, et al.
Hepatology
. 2015 Jun;
62(4):1227-36.
PMID: 26108984
Unlabelled: The intercellular adhesion molecule 1 (ICAM-1) is induced in mouse liver after bile duct ligation (BDL) and plays a key role in neutrophil-mediated liver injury in BDL mice. ICAM-1...
9.
Ketchem C, Khundmiri S, Gaweda A, Murray R, Clark B, Weinman E, et al.
Am J Physiol Renal Physiol
. 2015 May;
309(2):F109-19.
PMID: 25995109
Na+/H+ exchanger regulatory factor (NHERF1) plays a critical role in the renal transport of phosphate by binding to Na+-Pi cotransporter (NpT2a) in the proximal tubule. While the association between NpT2a...
10.
Grimm P, Lazo-Fernandez Y, Delpire E, Wall S, Dorsey S, Weinman E, et al.
J Clin Invest
. 2015 Apr;
125(5):2136-50.
PMID: 25893600
Thiazide diuretics are used to treat hypertension; however, compensatory processes in the kidney can limit antihypertensive responses to this class of drugs. Here, we evaluated compensatory pathways in SPAK kinase-deficient...