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Xiaofei E

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Articles 17
Citations 572
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Recent Articles
1.
E X, Kowalik T
Methods Mol Biol . 2021 Feb; 2244:247-264. PMID: 33555591
Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 screens enable virus-host genetic screens to be undertaken in a more robust manner than previously possible and has had a tremendous impact in...
2.
Zheng W, Xu Q, Zhang Y, E X, Gao W, Zhang M, et al.
Virol J . 2021 Jan; 17(1):199. PMID: 33384018
No abstract available.
3.
Zheng W, Xu Q, Zhang Y, E X, Gao W, Zhang M, et al.
Virol J . 2020 Dec; 17(1):192. PMID: 33298111
Background: In the past decades, researchers have demonstrated the critical role of Toll-like receptors (TLRs) in the innate immune system. They recognize viral components and trigger immune signal cascades to...
4.
Taher H, Mahyari E, Kreklywich C, Uebelhoer L, McArdle M, Mostrom M, et al.
PLoS Pathog . 2020 Nov; 16(11):e1008666. PMID: 33232376
Cytomegaloviruses (CMVs) are highly adapted to their host species resulting in strict species specificity. Hence, in vivo examination of all aspects of CMV biology employs animal models using host-specific CMVs....
5.
E X, Meraner P, Lu P, Perreira J, Aker A, McDougall W, et al.
Proc Natl Acad Sci U S A . 2019 Mar; 116(14):7043-7052. PMID: 30894498
A human cytomegalovirus (HCMV) pentameric glycoprotein complex (PC), gH-gL-UL128-UL130-UL131A, is necessary for viral infection of clinically relevant cell types, including epithelial cells, which are important for interhost transmission and disease....
6.
Bruggenwirth I, Moore C, Mahboub P, Thijssen M, E X, Leuvenink H, et al.
Transplant Direct . 2018 Dec; 4(11):e400. PMID: 30534591
Background: It remains controversial if arterial perfusion in addition to portal vein perfusion during machine preservation improves liver graft quality. Comparative studies using both techniques are lacking. We studied the...
7.
E X, Savidis G, Chin C, Wang S, Lu S, Brass A, et al.
J Virol . 2013 Dec; 88(4):2279-90. PMID: 24335308
Human cytomegalovirus (HCMV) genome replication requires host DNA damage responses (DDRs) and raises the possibility that DNA repair pathways may influence viral replication. We report here that a nucleotide excision...
8.
E X, Pickering M, Debatis M, Castillo J, Lagadinos A, Wang S, et al.
PLoS Pathog . 2011 May; 7(5):e1001342. PMID: 21589897
DNA damage resulting from intrinsic or extrinsic sources activates DNA damage responses (DDRs) centered on protein kinase signaling cascades. The usual consequences of inducing DDRs include the activation of cell...
9.
Oh S, E X, Hwang S, Liang C
Autophagy . 2009 Nov; 6(1):151-2. PMID: 19923915
Autophagy constitutes a major catabolic process for the quality control of internal proteins and organelles of eukaryotic cells, and is emerging as an essential part of the host antiviral defense....
10.
E X, Hwang S, Oh S, Lee J, Jeong J, Gwack Y, et al.
PLoS Pathog . 2009 Oct; 5(10):e1000609. PMID: 19816569
Gamma-herpesviruses (gammaHVs) have developed an interaction with their hosts wherein they establish a life-long persistent infection and are associated with the onset of various malignancies. One critical virulence factor involved...