Eduardo Esquenazi
Overview
Explore the profile of Eduardo Esquenazi including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
23
Citations
2634
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0
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Recent Articles
1.
Kissai M, Chin E, Martinez-Pena F, Sulpizio A, Stout E, Usui I, et al.
Bioorg Med Chem Lett
. 2024 Nov;
115:130007.
PMID: 39521150
Cyclic guanosine monophosphate (GMP)-adenosine monophosphate (AMP) synthase (cGAS) is an enzyme sensor of double-stranded DNA (dsDNA) that serves to trigger activation of the cGAS-stimulator of interferon genes (STING) pathway. Excessive...
2.
Mediouni S, Chinthalapudi K, Ekka M, Usui I, Jablonski J, Clementz M, et al.
mBio
. 2019 Feb;
10(1).
PMID: 30723126
The intrinsically disordered HIV-1 Tat protein binds the viral RNA transactivation response structure (TAR), which recruits transcriptional cofactors, amplifying viral mRNA expression. Limited Tat transactivation correlates with HIV-1 latency. Unfortunately,...
3.
Kinnel R, Esquenazi E, Leao T, Moss N, Mevers E, Pereira A, et al.
J Nat Prod
. 2017 Apr;
80(5):1514-1521.
PMID: 28448144
Genome sequencing of microorganisms has revealed a greatly increased capacity for natural products biosynthesis than was previously recognized from compound isolation efforts alone. Hence, new methods are needed for the...
4.
Quinn R, Nothias L, Vining O, Meehan M, Esquenazi E, Dorrestein P
Trends Pharmacol Sci
. 2016 Nov;
38(2):143-154.
PMID: 27842887
Molecular networking is a tandem mass spectrometry (MS/MS) data organizational approach that has been recently introduced in the drug discovery, metabolomics, and medical fields. The chemistry of molecules dictates how...
5.
Wang M, Carver J, Phelan V, Sanchez L, Garg N, Peng Y, et al.
Nat Biotechnol
. 2016 Aug;
34(8):828-837.
PMID: 27504778
The potential of the diverse chemistries present in natural products (NP) for biotechnology and medicine remains untapped because NP databases are not searchable with raw data and the NP community...
6.
He X, McLean J, Edlund A, Yooseph S, Hall A, Liu S, et al.
Proc Natl Acad Sci U S A
. 2014 Dec;
112(1):244-9.
PMID: 25535390
The candidate phylum TM7 is globally distributed and often associated with human inflammatory mucosal diseases. Despite its prevalence, the TM7 phylum remains recalcitrant to cultivation, making it one of the...
7.
Davis J, Fricke W, Hamann M, Esquenazi E, Dorrestein P, Hill R
Appl Environ Microbiol
. 2013 Sep;
79(22):7073-81.
PMID: 24014539
Sacoglossans are characterized by the ability to sequester functional chloroplasts from their algal diet through a process called kleptoplasty, enabling them to photosynthesize. The bacterial diversity associated with sacoglossans is...
8.
Gonzalez D, Xu Y, Yang Y, Esquenazi E, Liu W, Edlund A, et al.
J Proteomics
. 2012 May;
75(16):5069-5076.
PMID: 22641157
Many microbes can be cultured as single-species communities. Often, these colonies are controlled and maintained via the secretion of metabolites. Such metabolites have been an invaluable resource for the discovery...
9.
Esquenazi E, Daly M, Bahrainwala T, Gerwick W, Dorrestein P
Bioorg Med Chem
. 2011 Jul;
19(22):6639-44.
PMID: 21784647
Direct observation of halogenated natural products produced by different strains of marine cyanobacteria was accomplished by electrospray ionization and matrix assisted laser desorption ionization and gas phase separation via ion...
10.
Engene N, Choi H, Esquenazi E, Byrum T, Villa F, Cao Z, et al.
J Nat Prod
. 2011 Jul;
74(8):1737-43.
PMID: 21751786
The evolutionary relationships of cyanobacteria, as inferred by their SSU (16S) rRNA genes, were used as predictors of their potential to produce varied secondary metabolites. The evolutionary relatedness in geographically...