Eda Capkin
Overview
Explore the profile of Eda Capkin including associated specialties, affiliations and a list of published articles.
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7
Citations
14
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Recent Articles
1.
von Delft F, Ni X, Richardson R, Godoy A, Ferla M, Kikawa C, et al.
Res Sq
. 2025 Feb;
PMID: 39989958
The Zika viral protease NS2B-NS3 is essential for the cleavage of viral polyprotein precursor into individual structural and non-structural (NS) proteins and is therefore an attractive drug target. Generation of...
2.
Kutlu A, Capkin E, Adacan K, Yuce M
ACS Omega
. 2024 Dec;
9(50):49272-49282.
PMID: 39713689
FcγRI plays a crucial role in the effector function of IgG antibodies, interacting with the lower hinge region of IgG1 with nanomolar affinity. Binding occurs specifically in domain 2 (D2)...
3.
Aschenbrenner J, de Godoy A, Fairhead M, Tomlinson C, Winokan M, Balcomb B, et al.
bioRxiv
. 2024 Sep;
PMID: 39229067
Chikungunya virus (CHIKV) causes severe fever, rash and debilitating joint pain that can last for monthsor even years. Millions of people have been infected with CHIKV, mostly in low and...
4.
Ni X, Richardson R, Godoy A, de Godoy A, Ferla M, Kikawa C, et al.
bioRxiv
. 2024 May;
PMID: 38746305
The Zika viral protease NS2B-NS3 is essential for the cleavage of viral polyprotein precursor into individual structural and non-structural (NS) proteins and is therefore an attractive drug target. Generation of...
5.
Capkin E, Kutlu A, Yuce M
Heliyon
. 2023 Oct;
9(9):e19469.
PMID: 37809995
The controlled orientation of biomolecules on the sensor surface is crucial for achieving high sensitivity and accurate detection of target molecules in biosensing. FcγRI is an immune cell surface receptor...
6.
Capkin E, Kurt H, Gurel B, Bicak D, Akgun Bas S, Daglikoca D, et al.
Langmuir
. 2022 Nov;
38(48):14623-14634.
PMID: 36416530
Fc γ receptors (FcγRs) are one of the structures that can initiate effector function for monoclonal antibodies. FcγRIa has the highest affinity toward IgG1-type monoclonal antibodies among all FcγRs. In...
7.
Gurel B, Berksoz M, Capkin E, Parlar A, Pala M, Ozkan A, et al.
Pharmaceutics
. 2022 Aug;
14(8).
PMID: 36015197
Avastin is a humanized recombinant monoclonal antibody used to treat cancer by targeting VEGF-A to inhibit angiogenesis. SIMAB054, an Avastin biosimilar candidate developed in this study, showed a different charge...
8.
Kulabhusan P, Pishva P, Capkin E, Tambe P, Yuce M
Curr Med Chem
. 2022 Feb;
30(8):910-934.
PMID: 35156569
Viral infections can cause fatal illnesses to humans as well as animals. Early detection of viruses is therefore crucial to provide effective treatment to patients. Recently, the Covid-19 pandemic has...
9.
Ak G, Aksu D, Capkin E, Sari O, Kimiz Gebologlu I, Hamarat Sanlier S
Prep Biochem Biotechnol
. 2019 Nov;
50(3):215-225.
PMID: 31750758
Drug-loaded magnetic nanoparticles have been developed because of the advantages of specific drug targeting in cancer treatment. Pemetrexed (PEM) is a multi-targeting antifolate agent that is effective for the treatment...