Michael Fairhead
Overview
Explore the profile of Michael Fairhead including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
33
Citations
899
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
von Delft F, Ni X, Richardson R, Godoy A, Ferla M, Kikawa C, et al.
Res Sq
. 2025 Feb;
PMID: 39989958
The Zika viral protease NS2B-NS3 is essential for the cleavage of viral polyprotein precursor into individual structural and non-structural (NS) proteins and is therefore an attractive drug target. Generation of...
2.
Aschenbrenner J, de Godoy A, Fairhead M, Tomlinson C, Winokan M, Balcomb B, et al.
bioRxiv
. 2024 Sep;
PMID: 39229067
Chikungunya virus (CHIKV) causes severe fever, rash and debilitating joint pain that can last for monthsor even years. Millions of people have been infected with CHIKV, mostly in low and...
3.
Lee A, Amick I, Aschenbrenner J, Barr H, Benjamin J, Brandis A, et al.
bioRxiv
. 2024 Sep;
PMID: 39229055
A strategy for pandemic preparedness is the development of antivirals against a wide set of viral targets with complementary mechanisms of action. SARS-CoV-2 nsp3-mac1 is a viral macrodomain with ADP-ribosylhydrolase...
4.
Lithgo R, Tomlinson C, Fairhead M, Winokan M, Thompson W, Wild C, et al.
bioRxiv
. 2024 May;
PMID: 38746446
are the causative agents of paediatric hand-foot-and-mouth disease, and a target for pandemic preparedness due to the risk of higher order complications in a large-scale outbreak. The 2A protease of...
5.
Ni X, Richardson R, Godoy A, de Godoy A, Ferla M, Kikawa C, et al.
bioRxiv
. 2024 May;
PMID: 38746305
The Zika viral protease NS2B-NS3 is essential for the cleavage of viral polyprotein precursor into individual structural and non-structural (NS) proteins and is therefore an attractive drug target. Generation of...
6.
Godoy A, Mesquita N, Noske G, Gawriljuk V, Lithgo R, Balcomb B, et al.
bioRxiv
. 2024 May;
PMID: 38746241
The Zika virus (ZIKV), discovered in Africa in 1947, swiftly spread across continents, causing significant concern due to its recent association with microcephaly in newborns and Guillain-Barré syndrome in adults....
7.
Boby M, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson M, et al.
Science
. 2023 Nov;
382(6671):eabo7201.
PMID: 37943932
We report the results of the COVID Moonshot, a fully open-science, crowdsourced, and structure-enabled drug discovery campaign targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease. We discovered...
8.
Godoy A, Nakamura A, Douangamath A, Song Y, Noske G, Gawriljuk V, et al.
Nucleic Acids Res
. 2023 Apr;
51(10):5255-5270.
PMID: 37115000
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). The NSP15 endoribonuclease enzyme, known as NendoU, is highly conserved and plays a critical...
9.
Boskovic F, Zhu J, Tivony R, Ohmann A, Chen K, Alawami M, et al.
Nat Nanotechnol
. 2023 Jan;
18(3):290-298.
PMID: 36646828
Respiratory infections are the major cause of death from infectious disease worldwide. Multiplexed diagnostic approaches are essential as many respiratory viruses have indistinguishable symptoms. We created self-assembled DNA nanobait that...
10.
Coker J, Katis V, Fairhead M, Schwenzer A, Clemmensen S, Frandsen B, et al.
Front Bioeng Biotechnol
. 2022 May;
10:871933.
PMID: 35600892
Recombinant protein expression in eukaryotic insect cells is a powerful approach for producing challenging targets. However, due to incompatibility with standard baculoviral platforms and existing low-throughput methodology, the use of...