Eckart Bindewald
Overview
Explore the profile of Eckart Bindewald including associated specialties, affiliations and a list of published articles.
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40
Citations
1210
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Recent Articles
1.
Halman J, Satterwhite E, Smollett J, Bindewald E, Parlea L, Viard M, et al.
RNA Dis
. 2021 Jul;
4.
PMID: 34307841
The targeted and conditional activation of pharmaceuticals is an increasingly important feature in modern personalized medicine. Nucleic acid nanoparticles show tremendous potential in this exploit due to their programmability and...
2.
Zakrevsky P, Bindewald E, Shapiro B
DNA RNA Nanotechnol
. 2021 Jul;
3(1):11-13.
PMID: 34307831
No abstract available.
3.
Bliss N, Bindewald E, Shapiro B
RNA Biol
. 2020 Jun;
17(9):1324-1330.
PMID: 32476596
Secondary structure prediction approaches rely typically on models of equilibrium free energies that are themselves based on in vitro physical chemistry. Recent transcriptome-wide experiments of in vivo RNA structure based...
4.
Zakrevsky P, Kasprzak W, Heinz W, Wu W, Khant H, Bindewald E, et al.
Nanoscale
. 2020 Jan;
12(4):2555-2568.
PMID: 31932830
Using RNA as a material for nanoparticle construction provides control over particle size and shape at the nano-scale. RNA nano-architectures have shown promise as delivery vehicles for RNA interference (RNAi)...
5.
Zakrevsky P, Bindewald E, Humbertson H, Viard M, Dorjsuren N, Shapiro B
Nanomaterials (Basel)
. 2019 Apr;
9(4).
PMID: 30991728
Several varieties of small nucleic acid constructs are able to modulate gene expression via one of a number of different pathways and mechanisms. These constructs can be synthesized, assembled and...
6.
Bindewald E, Dai L, Kasprzak W, Kim T, Gu S, Shapiro B
Molecules
. 2018 Dec;
23(12).
PMID: 30558267
Cells frequently simultaneously express RNAs and cognate antisense transcripts without necessarily leading to the formation of RNA duplexes. Here, we present a novel transcriptome-wide experimental approach to ascertain the presence...
7.
Lu J, Bindewald E, Kasprzak W, Shapiro B
Bioinformatics
. 2018 Jun;
34(24):4297-4299.
PMID: 29912310
Summary: Creating clear, visually pleasing 2D depictions of RNA and DNA strands and their interactions is important to facilitate and communicate insights related to nucleic acid structure. Here we present...
8.
Zakrevsky P, Parlea L, Viard M, Bindewald E, Afonin K, Shapiro B
Methods Mol Biol
. 2017 Jul;
1632:303-324.
PMID: 28730448
RNA has gained great interest for use in biomedical and therapeutic applications. This is due in part to RNA's ability to perform multiple functions, including the regulation of endogenously expressed...
9.
Sharan R, Bindewald E, Kasprzak W, Shapiro B
Methods Mol Biol
. 2017 Jul;
1632:19-32.
PMID: 28730430
A variety of designed RNA ring structures (ranging from triangles to hexagonal rings) have been reported in the scientific literature. Designing self-assembling RNA ring structures from structural motifs is, however,...
10.
Halman J, Satterwhite E, Roark B, Chandler M, Viard M, Ivanina A, et al.
Nucleic Acids Res
. 2017 Jan;
45(4):2210-2220.
PMID: 28108656
We introduce a new concept that utilizes cognate nucleic acid nanoparticles which are fully complementary and functionally-interdependent to each other. In the described approach, the physical interaction between sets of...