Dylan H de Vries
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Explore the profile of Dylan H de Vries including associated specialties, affiliations and a list of published articles.
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9
Citations
915
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Recent Articles
1.
Kokkorakis M, Folkertsma P, van Dam S, Sirotin N, Taheri S, Chagoury O, et al.
EClinicalMedicine
. 2023 Nov;
64:102235.
PMID: 37936659
Background: Type 2 diabetes disproportionately affects individuals of non-White ethnicity through a complex interaction of multiple factors. Therefore, early disease detection and prediction are essential and require tools that can...
2.
Li S, Schmid K, de Vries D, Korshevniuk M, Losert C, Oelen R, et al.
Genome Biol
. 2023 Apr;
24(1):80.
PMID: 37072791
Background: Expression quantitative trait loci (eQTL) studies show how genetic variants affect downstream gene expression. Single-cell data allows reconstruction of personalized co-expression networks and therefore the identification of SNPs altering...
3.
van Dam S, Folkertsma P, Castela Forte J, de Vries D, Herrera Cunillera C, Gannamani R, et al.
Sci Rep
. 2023 Feb;
13(1):1351.
PMID: 36807592
The growing public interest in genetic risk scores for various health conditions can be harnessed to inspire preventive health action. However, current commercially available genetic risk scores can be deceiving...
4.
Oelen R, de Vries D, Brugge H, Gordon M, Vochteloo M, Ye C, et al.
Nat Commun
. 2022 Jun;
13(1):3267.
PMID: 35672358
The host's gene expression and gene regulatory response to pathogen exposure can be influenced by a combination of the host's genetic background, the type of and exposure time to pathogens....
5.
Vosa U, Claringbould A, Westra H, Bonder M, Deelen P, Zeng B, et al.
Nat Genet
. 2021 Sep;
53(9):1300-1310.
PMID: 34475573
Trait-associated genetic variants affect complex phenotypes primarily via regulatory mechanisms on the transcriptome. To investigate the genetics of gene expression, we performed cis- and trans-expression quantitative trait locus (eQTL) analyses...
6.
Spreckels J, Wejryd E, Marchini G, Jonsson B, de Vries D, Jenmalm M, et al.
Microorganisms
. 2021 Apr;
9(5).
PMID: 33923278
DSM 17938 supplementation reduces morbidities in very low birth weight infants (<1500 g), while the effect on extremely low birth weight infants (ELBW, <1000 g) is still questioned. In a...
7.
de Vries D, Matzaraki V, Bakker O, Brugge H, Westra H, Netea M, et al.
PLoS Pathog
. 2020 Apr;
16(4):e1008408.
PMID: 32251450
Candida bloodstream infection, i.e. candidemia, is the most frequently encountered life-threatening fungal infection worldwide, with mortality rates up to almost 50%. In the majority of candidemia cases, Candida albicans is...
8.
van der Wijst M, de Vries D, Brugge H, Westra H, Franke L
Genome Med
. 2018 Dec;
10(1):96.
PMID: 30567569
Only a small fraction of patients respond to the drug prescribed to treat their disease, which means that most are at risk of unnecessary exposure to side effects through ineffective...
9.
van der Wijst M, Brugge H, de Vries D, Deelen P, Swertz M, Franke L
Nat Genet
. 2018 Apr;
50(4):493-497.
PMID: 29610479
Genome-wide association studies have identified thousands of genetic variants that are associated with disease . Most of these variants have small effect sizes, but their downstream expression effects, so-called expression...