Dustin A Dikeman
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Explore the profile of Dustin A Dikeman including associated specialties, affiliations and a list of published articles.
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15
Citations
197
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Recent Articles
1.
Wang Y, Ahmadi M, Dikeman D, Youn C, Archer N
Front Immunol
. 2023 Jul;
14:1171934.
PMID: 37483624
is a leading cause of bacteremia, further complicated by the emergence of antibiotic-resistant strains such as methicillin-resistant (MRSA). A better understanding of host defense mechanisms is needed for the development...
2.
Youn C, Pontaza C, Wang Y, Dikeman D, Joyce D, Alphonse M, et al.
Sci Adv
. 2023 Jun;
9(24):eadf8748.
PMID: 37327341
is the leading cause of skin and soft tissue infections and is a major health burden due to the emergence of antibiotic-resistant strains. To address the unmet need of alternative...
3.
DeMourdant T, Rajkovic C, Tracz J, Perdomo-Pantoja A, Judy B, Hernandez V, et al.
Spine J
. 2023 May;
23(9):1389-1399.
PMID: 37247639
Background Context: Bacterial infection of spinal instrumentation is a significant challenge in spinal fusion surgery. Although the intraoperative local application of powdered vancomycin is common practice for mitigating infection, the...
4.
Youn C, Dikeman D, Chang E, Liu H, Nolan S, Alphonse M, et al.
Exp Dermatol
. 2022 Dec;
32(4):425-435.
PMID: 36461082
Phosphodiesterase 4 (PDE4) is highly expressed in keratinocytes and immune cells and promotes pro-inflammatory responses upon activation. The activity of PDE4 has been attributed to various inflammatory conditions, leading to...
5.
Gordon O, Dikeman D, Ortines R, Wang Y, Youn C, Mumtaz M, et al.
Microbiol Spectr
. 2022 Sep;
10(5):e0245121.
PMID: 36106881
Staphylococcus aureus is an important cause of various infections in humans, including bacteremia, skin and soft tissue infections, and infections associated with implanted medical devices. The emergence of hospital- and...
6.
Ordonez A, Parker M, Miller R, Plyku D, Ruiz-Bedoya C, Tucker E, et al.
JCI Insight
. 2022 Jan;
7(1).
PMID: 35014627
Tools for noninvasive detection of bacterial pathogens are needed but are not currently available for clinical use. We have previously shown that para-aminobenzoic acid (PABA) rapidly accumulates in a wide...
7.
Gordon O, Lee D, Liu B, Langevin B, Ordonez A, Dikeman D, et al.
Sci Transl Med
. 2021 Dec;
13(622):eabl6851.
PMID: 34851697
is a major human pathogen causing serious implant–associated infections. Combination treatment with rifampin (10 to 15 mg/kg per day), which has dose-dependent activity, is recommended to treat orthopedic implant–associated infections....
8.
Patrick G, Liu H, Alphonse M, Dikeman D, Youn C, Otterson J, et al.
J Clin Invest
. 2021 Mar;
131(5).
PMID: 33645549
IgE induced by type 2 immune responses in atopic dermatitis is implicated in the progression of atopic dermatitis to other allergic diseases, including food allergies, allergic rhinitis, and asthma. However,...
9.
Gordon O, Miller R, Thompson J, Ordonez A, Klunk M, Dikeman D, et al.
Dis Model Mech
. 2020 Jun;
13(7).
PMID: 32586832
Post-surgical implant-associated spinal infection is a devastating complication commonly caused by Biofilm formation is thought to reduce penetration of antibiotics and immune cells, contributing to chronic and difficult-to-treat infections. A...
10.
Wang Y, Ashbaugh A, Dikeman D, Zhang J, Ackerman N, Kim S, et al.
J Orthop Res
. 2020 Jan;
38(8):1800-1809.
PMID: 31975434
Orthopedic implant-associated infection (OIAI) is a major complication that leads to implant failure. In preclinical models of Staphylococcus aureus OIAI, osteomyelitis and septic arthritis, interleukin-1α (IL-1α), IL-1β, and tumor necrosis...