Dragana Dragoljevic
Overview
Explore the profile of Dragana Dragoljevic including associated specialties, affiliations and a list of published articles.
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27
Citations
1022
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Recent Articles
1.
Dragoljevic D, Lee M, Pernes G, Morgan P, Louis C, Shihata W, et al.
Clin Transl Immunology
. 2023 Apr;
12(4):e1446.
PMID: 37091327
Objectives: The leading cause of mortality in patients with rheumatoid arthritis is atherosclerotic cardiovascular disease (CVD). We have shown that murine arthritis impairs atherosclerotic lesion regression, because of cellular cholesterol...
2.
Hanssen N, Tikellis C, Pickering R, Dragoljevic D, Lee M, Block T, et al.
Biomed Pharmacother
. 2023 Mar;
158:114211.
PMID: 36916437
Methylglyoxal (MGO) is a reactive glucose metabolite linked to diabetic cardiovascular disease (CVD). MGO levels surge during intermittent hyperglycemia. We hypothesize that these MGO spikes contribute to atherosclerosis, and that...
3.
Dubrovsky L, Brichacek B, Prashant N, Pushkarsky T, Mukhamedova N, Fleetwood A, et al.
Cell Rep
. 2022 Nov;
41(8):111674.
PMID: 36417867
A possible explanation for chronic inflammation in HIV-infected individuals treated with anti-retroviral therapy is hyperreactivity of myeloid cells due to a phenomenon called "trained immunity." Here, we demonstrate that human...
4.
Lee M, Cooney O, Lin X, Nadarajah S, Dragoljevic D, Huynh K, et al.
Mol Metab
. 2022 May;
61:101514.
PMID: 35562083
Objectives: Dysregulation of cholesterol metabolism in the liver and hematopoietic stem and progenitor cells (HSPCs) promotes atherosclerosis development. Previously, it has been shown that HMG-CoA-Reductase (HMGCR), the rate-limiting enzyme in...
5.
Murphy A, Dragoljevic D, Natarajan P, Wang N
Thromb Haemost
. 2022 Apr;
122(9):1435-1442.
PMID: 35445383
Hematopoiesis is the process of blood production, essential for the continued supply of immune cells and red blood cells. However, the proliferative nature of hematopoietic stem cells (HSCs) renders them...
6.
Lee K, Achuthan A, de Souza D, Lupancu T, Binger K, Lee M, et al.
Cell Rep
. 2022 Apr;
39(3):110719.
PMID: 35443173
Metabolic adaptations can directly influence the scope and scale of macrophage activation and polarization. Here we explore the impact of type I interferon (IFNβ) on macrophage metabolism and its broader...
7.
Dragoljevic D, Veiga C, Michell D, Shihata W, Al-Sharea A, Head G, et al.
Biomed Pharmacother
. 2021 Jul;
139:111668.
PMID: 34243630
Metabolic Syndrome (MetS) is a complex and multifactorial condition often characterised by obesity, hypertension, hyperlipidaemia, insulin resistance, glucose intolerance and fasting hyperglycaemia. Collectively, MetS can increase the risk of atherosclerotic-cardiovascular...
8.
Veiga C, Lawrence E, Murphy A, Herold M, Dragoljevic D
Cancers (Basel)
. 2021 Apr;
13(8).
PMID: 33921778
The development of myelodysplasia syndromes (MDS) is multiphasic and can be driven by a plethora of genetic mutations and/or abnormalities. MDS is characterized by a hematopoietic differentiation block, evidenced by...
9.
Lee M, Kraakman M, Dragoljevic D, Hanssen N, Flynn M, Al-Sharea A, et al.
Arterioscler Thromb Vasc Biol
. 2021 Jan;
41(3):1167-1178.
PMID: 33441028
Objective: People with diabetes are at a significantly higher risk of cardiovascular disease, in part, due to accelerated atherosclerosis. Diabetic subjects have increased number of platelets that are activated, more...
10.
Dragoljevic D, Lee M, Louis C, Shihata W, Kraakman M, Hansen J, et al.
Clin Transl Immunology
. 2020 Nov;
9(11):e1206.
PMID: 33204425
Objectives: Rheumatoid arthritis (RA), an inflammatory joint disorder, independently increases the risk of cardiovascular disease (CVD). IL-1β contributes to both RA and CVD. We hypothesised that inhibiting IL-1 signalling with...