Dorit Ben-Shachar
Overview
Explore the profile of Dorit Ben-Shachar including associated specialties, affiliations and a list of published articles.
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49
Citations
1142
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Recent Articles
11.
Ben-Shachar D, Ene H
Biol Psychiatry
. 2017 Oct;
83(9):770-779.
PMID: 28965983
The neurobiology of psychiatric disorders is still unclear, although changes in multiple neuronal systems, specifically the dopaminergic, glutamatergic, and gamma-aminobutyric acidergic systems as well as abnormalities in synaptic plasticity and...
12.
Robicsek O, Ene H, Karry R, Ytzhaki O, Asor E, McPhie D, et al.
Schizophr Bull
. 2017 Jun;
44(2):432-442.
PMID: 28586483
Dysfunction of mitochondria, key players in various essential cell processes, has been repeatedly reported in schizophrenia (SZ). Recently, several studies have reported functional recovery and cellular viability following mitochondrial transplantation,...
13.
Mitochondrial multifaceted dysfunction in schizophrenia; complex I as a possible pathological target
Ben-Shachar D
Schizophr Res
. 2016 Nov;
187:3-10.
PMID: 27802911
Mitochondria are key players in various essential cellular processes beyond being the main energy supplier of the cell. Accordingly, they are involved in neuronal synaptic transmission, neuronal growth and sprouting...
14.
Asor E, Ben-Shachar D
World J Psychiatry
. 2016 Sep;
6(3):294-302.
PMID: 27679768
It is generally assumed that behavior results from an interaction between susceptible genes and environmental stimuli during critical life stages. The present article reviews the main theoretical and practical concepts...
15.
Bergman O, Ben-Shachar D
Can J Psychiatry
. 2016 Jul;
61(8):457-69.
PMID: 27412728
Mitochondria are key players in the generation and regulation of cellular bioenergetics, producing the majority of adenosine triphosphate molecules by the oxidative phosphorylation system (OXPHOS). Linked to numerous signaling pathways...
16.
Asor E, Stempler S, Avital A, Klein E, Ruppin E, Ben-Shachar D
Eur Neuropsychopharmacol
. 2015 Aug;
25(10):1695-705.
PMID: 26271721
Previously, we showed that a transient early-in-life interference with the expression of multiple genes by mithramycin (MTR) followed by later-in-life exposure to chronic stress, leads to a "daring" and novelty...
17.
Ben-Shachar D, Suss-Toby E, Robicsek O
Methods Mol Biol
. 2015 Jan;
1265:425-39.
PMID: 25634294
Mitochondria, similar to living cells and organelles, have negative membrane potential and can therefore accumulate permeable lipophilic cations. Those cations which exhibit fluorescence activity after accumulation into energized systems are...
18.
Shulman E, Belakhov V, Wei G, Kendall A, Meyron-Holtz E, Ben-Shachar D, et al.
J Biol Chem
. 2013 Dec;
289(4):2318-30.
PMID: 24302717
There is compelling evidence that aminoglycoside (AG) antibiotics can induce the mammalian ribosome to suppress disease-causing nonsense mutations and partially restore the expression of functional proteins. However, prolonged AG treatment...
19.
Kaphzan H, Ben-Shachar D, Klein E
Int J Neuropsychopharmacol
. 2013 Nov;
17(2):337-40.
PMID: 24229565
Negative symptoms in schizophrenia are associated with decreased dopaminergic activity in the prefrontal cortex (PFC). It is hypothesized that increasing dopamine levels would alleviate negative symptoms. Termination of dopamine activity...
20.
Asor E, Ben-Shachar D
World J Psychiatry
. 2013 Nov;
2(6):124-33.
PMID: 24175178
Schizophrenia is a severe mental disorder, characterized by behavioral, emotional and cognitive disturbances, which commonly follows a chronic course. Diagnostic accuracy, management plans, treatment evaluation and prognosis are dependent on...