Donna M Poscablo
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Explore the profile of Donna M Poscablo including associated specialties, affiliations and a list of published articles.
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5
Citations
33
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Recent Articles
1.
Poscablo D, Worthington A, Smith-Berdan S, Rommel M, Manso B, Adili R, et al.
Cell
. 2024 May;
187(12):3090-3107.e21.
PMID: 38749423
Platelet dysregulation is drastically increased with advanced age and contributes to making cardiovascular disorders the leading cause of death of elderly humans. Here, we reveal a direct differentiation pathway from...
2.
Martin E, Rodriguez Y Baena A, Reggiardo R, Worthington A, Mattingly C, Poscablo D, et al.
Stem Cells
. 2023 Mar;
41(5):520-539.
PMID: 36945732
Epigenetic mechanisms regulate the multilineage differentiation capacity of hematopoietic stem cells (HSCs) into a variety of blood and immune cells. Mapping the chromatin dynamics of functionally defined cell populations will...
3.
Worthington A, Cool T, Poscablo D, Hussaini A, Beaudin A, Forsberg E
Development
. 2022 Jan;
149(8).
PMID: 35072209
Tissue-resident lymphoid cells (TLCs) span the spectrum of innate-to-adaptive immune function. Unlike traditional, circulating lymphocytes that are continuously generated from hematopoietic stem cells (HSCs), many TLCs are of fetal origin...
4.
Poscablo D, Forsberg E
Adv Geriatr Med Res
. 2022 Jan;
3(4).
PMID: 35037001
Platelets provide life-saving functions by halting external and internal bleeding. There is also a dark side to platelet biology, however. Recent reports provide evidence for increased platelet reactivity during aging...
5.
Poscablo D, Worthington A, Smith-Berdan S, Forsberg E
Stem Cell Reports
. 2021 May;
16(6):1598-1613.
PMID: 34019813
Age-related morbidity is associated with a decline in hematopoietic stem cell (HSC) function, but the mechanisms of HSC aging remain unclear. We performed heterochronic HSC transplants followed by quantitative analysis...