Dong-Ke Yu
Overview
Explore the profile of Dong-Ke Yu including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
164
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0
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Recent Articles
1.
Yang Y, Li W, Ren L, Yang H, Zhang Y, Zhang S, et al.
Acta Pharmacol Sin
. 2023 Sep;
45(1):209-222.
PMID: 37749236
Glioblastoma (GBM) is the most common malignant tumor in the brain with temozolomide (TMZ) as the only approved chemotherapy agent. GBM is characterized by susceptibility to radiation and chemotherapy resistance...
2.
Lu Z, Shan Q, Hu S, Zhao Y, Zhang G, Zhu M, et al.
Bioorg Med Chem
. 2021 Oct;
49:116438.
PMID: 34610571
Liver fibrosis is one of the most common pathological consequences of chronic liver diseases (CLD). To develop effective antifibrotic strategies, a novel class of 1-(substituted phenyl)-1,8-naphthalidine-3-carboxamide derivatives were designed and...
3.
Zhang Y, Yang X, Yu D, Xiao H, Du J
J Pharm Pharmacol
. 2021 Apr;
73(7):986-995.
PMID: 33877365
Objectives: To explore the potential molecular mechanism underlying the effect of green tea extract (TE), rich in tea polyphenols (TPs), on improving alcohol-induced liver injury. Methods: Mice were intragastrically treated...
4.
Xue L, Zou X, Yang X, Peng F, Yu D, Du J
Exp Neurol
. 2020 Jan;
326:113176.
PMID: 31926167
Epidemiological studies suggest that chronic periodontitis (CP) is closely associated with the incidence and progression of cognitive impairment. The present study investigated the causal relationship between CP and cognitive decline...
5.
Ge M, Liu H, Zhang N, Niu W, Lu Z, Bao Y, et al.
Br J Pharmacol
. 2019 Oct;
177(2):372-387.
PMID: 31621893
Background And Purpose: This study investigates the antifibrotic activities and potential mechanisms of costunolide (COS), a natural sesquiterpene compound. Experimental Approach: Rats subjected to bile duct ligation and mice challenged...
6.
Ge M, Niu W, Ren J, Cai S, Yu D, Liu H, et al.
Acta Pharmacol Sin
. 2018 Dec;
40(7):895-907.
PMID: 30573812
The manipulation of bile acid (BA) homeostasis by blocking the ileal apical Na-dependent bile salt transporter (ASBT/SLC10A2) may have therapeutic effects in nonalcoholic fatty liver disease. We developed a novel...
7.
Yu D, Zhang C, Zhao S, Zhang S, Zhang H, Cai S, et al.
Acta Pharmacol Sin
. 2015 Apr;
36(4):473-82.
PMID: 25832428
Aim: (-)-Epigallocatechin-3-gallate (EGCG) is one of the most abundant polyphenols in green tea with strong antioxidant activity and various therapeutic effects. In this study, we investigated the anti-fibrotic effects of...
8.
Bai X, Yu D, Wang J, Zhang H, He H, Shao R, et al.
Bioorg Med Chem Lett
. 2012 Oct;
22(22):6947-51.
PMID: 23036956
A series of novel 1-acyl-3-amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole derivatives were designed and synthesized. These derivatives were initially evaluated for their in vitro anticancer activity against human colon carcinoma HCT-116 cell line, and compounds...
9.
Chen Y, Ji W, Du J, Yu D, He Y, Yu C, et al.
Biomed Pharmacother
. 2009 Nov;
64(4):291-5.
PMID: 19932586
Available evidence indicates that brown algae may be beneficial for the treatment of high blood pressure. Our recent study demonstrated that low molecular mass potassium alginate (L-PA), one of the...
10.
Ji W, Chen Y, Du J, Yu D, Zheng X, Yang F, et al.
Sichuan Da Xue Xue Bao Yi Xue Ban
. 2009 Sep;
40(4):694-6, 703.
PMID: 19764575
Objective: To investigate the effect of low molecular weight potassium alginate (L-PA) on blood pressures in spontaneously hypertensive rats (SHRs) and its pharmacokinetics characteristics in mice. Methods: The systolic blood...