Dmitry V Tsyganov
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Explore the profile of Dmitry V Tsyganov including associated specialties, affiliations and a list of published articles.
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11
Citations
49
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Recent Articles
1.
Tsyganov D, Samet A, Silyanova E, Ushkarov V, Varakutin A, Chernysheva N, et al.
ACS Omega
. 2022 Feb;
7(4):3369-3383.
PMID: 35128247
Derivatives of natural allylpolyalkoxybenzenes conjugated to triphenylphosphonium (TPP) cations by aliphatic linkers of three, six, seven, and eight atoms were synthesized to examine the role of the polyalkoxybenzene pharmacophore, TPP...
2.
Semenova M, Demchuk D, Tsyganov D, Chernysheva N, Samet A, Silyanova E, et al.
ACS Comb Sci
. 2018 Nov;
20(12):700-721.
PMID: 30452225
A series of both novel and reported combretastatin analogues, including diarylpyrazoles, -isoxazoles, -1,2,3-triazoles, and -pyrroles, were synthesized via improved protocols to evaluate their antimitotic antitubulin activity using in vivo sea...
3.
Semenov V, Tsyganov D, Semenova M, Chuprov-Netochin R, Raihstat M, Konyushkin L, et al.
J Nat Prod
. 2016 Apr;
79(5):1429-38.
PMID: 27100701
A concise six-step protocol for the synthesis of isoflavone glaziovianin A (GVA) and its alkoxyphenyl derivatives 9 starting with readily available plant metabolites from dill and parsley seeds was developed....
4.
Tsyganov D, Krayushkin M, Konyushkin L, Strelenko Y, Semenova M, Semenov V
J Nat Prod
. 2016 Feb;
79(4):923-8.
PMID: 26910798
Analogues of the bioactive natural alkoxynaphthalene pycnanthulignene D were synthesized by an efficient method. The starting plant allylalkoxybenzenes (1) are easily available from the plant essential oils of sassafras, dill,...
5.
Semenova M, Tsyganov D, Malyshev O, Ershov O, Bardasov I, Semenov R, et al.
Bioorg Med Chem Lett
. 2014 Jul;
24(16):3914-8.
PMID: 24997684
A series of polyalkoxy substituted 7-hydroxy- and 7-methoxy-4-aryl-4H-chromenes were evaluated using the sea urchin embryo model to yield several compounds exhibiting potent antimitotic microtubule destabilizing activity. Data obtained by the...
6.
Tsyganov D, Khrustalev V, Konyushkin L, Raihstat M, Firgang S, Semenov R, et al.
Eur J Med Chem
. 2014 Jan;
73:112-25.
PMID: 24388833
A regioselective synthesis of both 5-amino- and 3-aminodiarylisoxazoles substituted with polyalkoxyaryl pharmacophores has been validated. Starting materials for the synthetic scheme were easily available from plant extracts. The targeted molecules...
7.
Tsyganov D, Konyushkin L, Karmanova I, Firgang S, Strelenko Y, Semenova M, et al.
J Nat Prod
. 2013 Aug;
76(8):1485-91.
PMID: 23924236
We have synthesized a series of novel cis-restricted 4,5-polyalkoxydiaryl-3-aminopyrazole analogues of combretastatins via short synthetic sequences using building blocks isolated from dill and parsley seed extracts. The resulting compounds were...
8.
Chernysheva N, Tsyganov D, Philchenkov A, Zavelevich M, Kiselyov A, Semenov R, et al.
Bioorg Med Chem Lett
. 2012 Feb;
22(7):2590-3.
PMID: 22370267
A series of novel 4-oxa-podophyllotoxin derivatives 7 featuring the intact lactone ring D and various substituents in rings B and E has been synthesized and evaluated in a phenotypic sea...
9.
Semenova M, Kiselyov A, Tsyganov D, Konyushkin L, Firgang S, Semenov R, et al.
J Med Chem
. 2011 Sep;
54(20):7138-49.
PMID: 21916509
A series of 4-azapodophyllotoxin derivatives with modified rings B and E have been synthesized using allylpolyalkoxybenzenes from parsley seed oil. The targeted molecules were evaluated in vivo in a phenotypic...
10.
Semenov V, Kiselyov A, Titov I, Sagamanova I, Ikizalp N, Chernysheva N, et al.
J Nat Prod
. 2010 Nov;
73(11):1796-802.
PMID: 21049975
No abstract available.