Divya Nandakumar
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Explore the profile of Divya Nandakumar including associated specialties, affiliations and a list of published articles.
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16
Citations
785
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Recent Articles
1.
Balasubramanian S, Sankar J, Dhanalakshmi K, Lakshan Raj S, Nandakumar D, Ramanan A, et al.
Indian Pediatr
. 2023 Mar;
60(5):377-380.
PMID: 36896750
Objective: Identifying clinical and laboratory indicators that differentiate multisystem inflam-matory syndrome in children (MIS-C) apart from other febrile diseases in a tropical hospital setting. Methods: Review of hospital records done...
2.
Morgens D, Nandakumar D, Didychuk A, Yang K, Glaunsinger B
PLoS Pathog
. 2022 Jan;
18(1):e1010236.
PMID: 35041709
While traditional methods for studying large DNA viruses allow the creation of individual mutants, CRISPR/Cas9 can be used to rapidly create thousands of mutant dsDNA viruses in parallel, enabling the...
3.
Ehrenberg A, Moehle E, Brook C, Doudna Cate A, Witkowsky L, Sachdeva R, et al.
PLoS One
. 2021 May;
16(5):e0251296.
PMID: 34038425
Regular surveillance testing of asymptomatic individuals for SARS-CoV-2 has been center to SARS-CoV-2 outbreak prevention on college and university campuses. Here we describe the voluntary saliva testing program instituted at...
4.
Hartenian E, Nandakumar D, Lari A, Ly M, Tucker J, Glaunsinger B
J Biol Chem
. 2020 Jul;
295(37):12910-12934.
PMID: 32661197
Few human pathogens have been the focus of as much concentrated worldwide attention as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19. Its emergence into the human...
5.
Singh A, Pandey M, Nandakumar D, Raney K, Yin Y, Patel S
EMBO J
. 2020 Feb;
39(6):e103367.
PMID: 32037587
The proofreading exonuclease activity of replicative DNA polymerase excises misincorporated nucleotides during DNA synthesis, but these events are rare. Therefore, we were surprised to find that T7 replisome excised nearly...
6.
Nandakumar D, Glaunsinger B
PLoS Pathog
. 2019 May;
15(5):e1007774.
PMID: 31095645
The structural proteins of DNA viruses are generally encoded by late genes, whose expression relies on recruitment of the host transcriptional machinery only after the onset of viral genome replication....
7.
Koh H, Roy R, Sorokina M, Tang G, Nandakumar D, Patel S, et al.
Mol Cell
. 2018 May;
70(4):695-706.e5.
PMID: 29775583
We provide a comprehensive analysis of transcription in real time by T7 RNA Polymerase (RNAP) using single-molecule fluorescence resonance energy transfer by monitoring the entire life history of transcription initiation,...
8.
Seyfried N, Dammer E, Swarup V, Nandakumar D, Duong D, Yin L, et al.
Cell Syst
. 2016 Dec;
4(1):60-72.e4.
PMID: 27989508
Here, we report proteomic analyses of 129 human cortical tissues to define changes associated with the asymptomatic and symptomatic stages of Alzheimer's disease (AD). Network analysis revealed 16 modules of...
9.
Ramachandran A, Basu U, Sultana S, Nandakumar D, Patel S
Nucleic Acids Res
. 2016 Dec;
45(2):861-874.
PMID: 27903899
Human mitochondrial DNA is transcribed by POLRMT with the help of two initiation factors, TFAM and TFB2M. The current model postulates that the role of TFAM is to recruit POLRMT...
10.
Ramachandran A, Nandakumar D, Deshpande A, Lucas T, R-Bhojappa R, Tang G, et al.
J Biol Chem
. 2016 Jun;
291(32):16828-39.
PMID: 27311715
Primases use single-stranded (ss) DNAs as templates to synthesize short oligoribonucleotide primers that initiate lagging strand DNA synthesis or reprime DNA synthesis after replication fork collapse, but the origin of...