Diana Reyes-Garau
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Explore the profile of Diana Reyes-Garau including associated specialties, affiliations and a list of published articles.
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9
Citations
132
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Recent Articles
1.
Chamorro-Jorganes A, Profitos-Peleja N, Recasens-Zorzo C, Valero J, Reyes-Garau D, Magnano L, et al.
Neoplasia
. 2025 Feb;
61:101131.
PMID: 39914169
A significant proportion of diffuse large B cell lymphoma (DLBCL) and follicular lymphoma (FL) cases harbor a gain-of-function, heterozygous somatic mutation of the methyltransferase gene EZH2. While this factor is...
2.
Ribeiro M, Profitos-Peleja N, Santos J, Blecua P, Reyes-Garau D, Armengol M, et al.
Front Immunol
. 2023 May;
14:1130052.
PMID: 37153563
Background: Immunotherapy-based regimens have considerably improved the survival rate of B-cell non-Hodgkin lymphoma (B-NHL) patients in the last decades; however, most disease subtypes remain almost incurable. TG-1801, a bispecific antibody...
3.
Quinet G, Xolalpa W, Reyes-Garau D, Profitos-Peleja N, Azkargorta M, Ceccato L, et al.
Cancers (Basel)
. 2022 Feb;
14(4).
PMID: 35205670
Protein ubiquitylation coordinates crucial cellular events in physiological and pathological conditions. A comparative analysis of the ubiquitin proteome from bortezomib (BTZ)-sensitive and BTZ-resistant mantle cell lymphoma (MCL) revealed an enrichment...
4.
Ribeiro M, Reyes-Garau D, Vinyoles M, Profitos Peleja N, Santos J, Armengol M, et al.
Clin Cancer Res
. 2021 Sep;
27(23):6591-6601.
PMID: 34551904
Purpose: Despite the remarkable activity of BTK inhibitors (BTKi) in relapsed B-cell non-Hodgkin lymphoma (B-NHL), no clinically-relevant biomarker has been associated to these agents so far. The relevance of phosphoproteomic...
5.
Lunazzi G, Buxade M, Riera-Borrull M, Higuera L, Bonnin S, Huerga Encabo H, et al.
J Immunol
. 2021 May;
206(11):2652-2667.
PMID: 34031145
The ability of innate immune cells to respond to pathogen-associated molecular patterns across a wide range of intensities is fundamental to limit the spreading of infections. Studies on transcription responses...
6.
Gonzalez-Santamarta M, Quinet G, Reyes-Garau D, Sola B, Roue G, Rodriguez M
Adv Exp Med Biol
. 2020 Apr;
1233:153-174.
PMID: 32274756
Since its introduction in the clinics in early 2000s, the proteasome inhibitor bortezomib (BTZ) significantly improved the prognosis of patients with multiple myeloma (MM) and mantle cell lymphoma (MCL), two...
7.
Ribeiro M, Reyes-Garau D, Armengol M, Fernandez-Serrano M, Roue G
Front Genet
. 2019 Nov;
10:986.
PMID: 31681423
In the last 10 years, major advances have been made in the diagnosis and development of selective therapies for several blood cancers, including B-cell non-Hodgkin lymphoma (B-NHL), a heterogeneous group...
8.
Reyes-Garau D, Ribeiro M, Roue G
Cancers (Basel)
. 2019 Oct;
11(10).
PMID: 31581671
Alterations in protein-protein and DNA-protein interactions and abnormal chromatin remodeling are a major cause of uncontrolled gene transcription and constitutive activation of critical signaling pathways in cancer cells. Multiple epigenetic...
9.
Mendoza P, Martinez-Martin N, Bovolenta E, Reyes-Garau D, Hernansanz-Agustin P, Delgado P, et al.
Sci Signal
. 2018 May;
11(532).
PMID: 29844052
Upon antigen recognition within peripheral lymphoid organs, B cells interact with T cells and other immune cells to transiently form morphological structures called germinal centers (GCs), which are required for...
10.
Borroto A, Reyes-Garau D, Jimenez M, Carrasco E, Moreno B, Martinez-Pasamar S, et al.
Sci Transl Med
. 2016 Dec;
8(370):370ra184.
PMID: 28003549
Modulating T cell activation is critical for treating autoimmune diseases but requires avoiding concomitant opportunistic infections. Antigen binding to the T cell receptor (TCR) triggers the recruitment of the cytosolic...