Devadharshini Jeevarajah
Overview
Explore the profile of Devadharshini Jeevarajah including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
20
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Recent Articles
1.
Jose J, Law R, Leung E, Wai D, Akhlaghi H, Chandrashekaran I, et al.
Eur J Med Chem
. 2023 Sep;
261:115786.
PMID: 37716187
Perforin is a pore-forming protein whose normal function enables cytotoxic T and natural killer (NK) cells to kill virus-infected and transformed cells. Conversely, unwanted perforin activity can also result in...
2.
Aryal P, Devkota S, Jeevarajah D, Law R, Payne R, Bhusal R, et al.
J Biol Chem
. 2022 Aug;
298(10):102382.
PMID: 35973511
Class A tick evasins are natural chemokine-binding proteins that block the signaling of multiple chemokines from the CC subfamily through their cognate receptors, thus suppressing leukocyte recruitment and inflammation. Development...
3.
Quek A, Mazzitelli B, Wu G, Leung E, Caradoc-Davies T, Lloyd G, et al.
J Mol Biol
. 2019 Jul;
431(19):3804-3813.
PMID: 31295457
Plasminogen (Plg)-binding M protein (PAM) is a group A streptococcal cell surface receptor that is crucial for bacterial virulence. Previous studies revealed that, by binding to the kringle 2 (KR2)...
4.
Law R, Wu G, Leung E, Hidaka K, Quek A, Caradoc-Davies T, et al.
Blood Adv
. 2018 Jan;
1(12):766-771.
PMID: 29296720
The zymogen protease plasminogen and its active form plasmin perform key roles in blood clot dissolution, tissue remodeling, cell migration, and bacterial pathogenesis. Dysregulation of the plasminogen/plasmin system results in...