Denise Glaise
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Explore the profile of Denise Glaise including associated specialties, affiliations and a list of published articles.
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25
Citations
1391
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Recent Articles
1.
Dubois-Pot-Schneider H, Aninat C, Kattler K, Fekir K, Jarnouen K, Cerec V, et al.
Cells
. 2022 Jul;
11(15).
PMID: 35892596
Dimethyl sulfoxide (DMSO) is used to sustain or favor hepatocyte differentiation in vitro. Thus, DMSO is used in the differentiation protocol of the HepaRG cells that present the closest drug-metabolizing...
2.
Desoteux M, Louis C, Bevant K, Glaise D, Coulouarn C
Cancers (Basel)
. 2021 Nov;
13(22).
PMID: 34830779
Hepatocellular carcinoma (HCC) is a deadly cancer worldwide as a result of a frequent late diagnosis which limits the therapeutic options. Tumor progression in HCC is closely correlated with the...
3.
Fekir K, Dubois-Pot-Schneider H, Desert R, Daniel Y, Glaise D, Rauch C, et al.
Cancer Res
. 2019 Mar;
79(8):1869-1883.
PMID: 30837223
Human hepatocellular carcinoma (HCC) heterogeneity promotes recurrence and therapeutic resistance. We recently demonstrated that inflammation favors hepatocyte retrodifferentiation into progenitor cells. Here, we identify the molecular effectors that induce metabolic...
4.
Dornas W, Glaise D, Bodin A, Sharanek A, Burban A, Le Guillou D, et al.
J Cell Physiol
. 2018 Sep;
234(1):122-133.
PMID: 30191979
Previous studies have shown that gut-derived bacterial endotoxins contribute in the progression of simple steatosis to steatohepatitis, although the mechanism(s) remains inaccurate to date. As hepatic stellate cells (HSC) play...
5.
Ancey P, Ecsedi S, Lambert M, Talukdar F, Cros M, Glaise D, et al.
Stem Cell Reports
. 2017 Jun;
9(1):264-278.
PMID: 28648900
Understanding the processes that govern liver progenitor cell differentiation has important implications for the design of strategies targeting chronic liver diseases, whereby regeneration of liver tissue is critical. Although DNA...
6.
Quesnot N, Rondel K, Audebert M, Martinais S, Glaise D, Morel F, et al.
Mutagenesis
. 2015 Aug;
31(1):43-50.
PMID: 26282955
The in situ detection of γH2AX was recently reported to be a promising biomarker of genotoxicity. In addition, the human HepaRG hepatoma cells appear to be relevant for investigating hepatic...
7.
Dubois-Pot-Schneider H, Fekir K, Coulouarn C, Glaise D, Aninat C, Jarnouen K, et al.
Hepatology
. 2014 Aug;
60(6):2077-90.
PMID: 25098666
Unlabelled: Human hepatocellular carcinoma (HCC) heterogeneity promotes recurrence and resistance to therapies. Recent studies have reported that HCC may be derived not only from adult hepatocytes and hepatoblasts but also...
8.
Laurent V, Glaise D, Nubel T, Gilot D, Corlu A, Loyer P
Methods Mol Biol
. 2013 Mar;
987:295-314.
PMID: 23475687
The metabolically competent hepatocyte-like human HepaRG cells represent a suitable alternative in vitro cell model to human primary hepatocytes. Here, we describe the culture procedure required to expand progenitor HepaRG...
9.
Coulouarn C, Corlu A, Glaise D, Guenon I, Thorgeirsson S, Clement B
Cancer Res
. 2012 Mar;
72(10):2533-42.
PMID: 22419664
Many solid malignant tumors arise on a background of inflamed and/or fibrotic tissues, features that are found in more than 80% hepatocellular carcinomas (HCC). Activated hepatic stellate cells (HSC) play...
10.
Madec S, Cerec V, Plee-Gautier E, Antoun J, Glaise D, Salaun J, et al.
Drug Metab Dispos
. 2011 Jul;
39(10):1987-96.
PMID: 21778351
Fatty acid microsomal ω-oxidation involves cytochrome P450 enzymes. Some of them belonging to the CYP4F3 family are mainly expressed in the liver, making this organ a major player in energy...