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Cedric Coulouarn

Explore the profile of Cedric Coulouarn including associated specialties, affiliations and a list of published articles. Areas
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Articles 80
Citations 2847
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Recent Articles
1.
Mannini A, Pastore M, Giachi A, Correnti M, Spinola Lasso E, Lottini T, et al.
Liver Int . 2024 Dec; 45(1):e16208. PMID: 39726234
Background & Aims: GD2, a member of the ganglioside (GS) family (sialic acid-containing glycosphingolipids), is a potential biomarker of cancer stem cells (CSC) in several tumours. However, the possible role...
2.
Gonzalez-Sanchez E, Vaquero J, Caballero-Diaz D, Grzelak J, Fuste N, Bertran E, et al.
J Pathol . 2024 Jun; 263(4-5):482-495. PMID: 38872438
Liver fibrosis is the consequence of chronic liver injury in the presence of an inflammatory component. Although the main executors of this activation are known, the mechanisms that lead to...
3.
Doudnikoff C, Leclerc D, Angenard G, Gilot D, Coulouarn C, Mouriaux F
Mol Vis . 2024 Apr; 30:160-166. PMID: 38601020
Purpose: Uveal melanoma (UM) is a deadly cancer with limited therapeutic options. At advanced stages, UM cells metastasize almost exclusively into the liver, where targeting metastatic UM cells remain a...
4.
Papoutsoglou P, Pineau R, Leroux R, Louis C, LHaridon A, Foretek D, et al.
EMBO Rep . 2024 Feb; 25(3):1022-1054. PMID: 38332153
Cholangiocarcinoma is a devastating liver cancer characterized by high aggressiveness and therapy resistance, resulting in poor prognosis. Long non-coding RNAs and signals imposed by oncogenic pathways, such as transforming growth...
5.
Louis C, Ferlier T, Leroux R, Pineau R, Desoteux M, Papoutsoglou P, et al.
JHEP Rep . 2023 Nov; 5(12):100900. PMID: 38023605
Background & Aims: Intrahepatic cholangiocarcinoma (iCCA) is a deadly cancer worldwide with an increasing incidence and limited therapeutic options. Therefore, there is an urgent need to open the field to...
6.
Le Breton C, Coulouarn C
Cancers (Basel) . 2023 Sep; 15(17). PMID: 37686658
Liver cancers, including hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), are deadly cancers that have risen in frequency globally and have limited curative therapeutic options [...].
7.
Desoteux M, Maillot B, Bevant K, Ferlier T, Leroux R, Angenard G, et al.
FEBS Open Bio . 2023 May; 13(7):1278-1290. PMID: 37195148
Therapeutic targeting of the transforming growth factor beta (TGFβ) pathway in cancer represents a clinical challenge since TGFβ exhibits either tumor suppressive or tumor promoting properties, depending on the tumor...
8.
Calvisi D, Boulter L, Vaquero J, Saborowski A, Fabris L, Rodrigues P, et al.
Nat Rev Gastroenterol Hepatol . 2023 Feb; 20(7):462-480. PMID: 36755084
Cholangiocarcinoma (CCA) is a rare malignancy that develops at any point along the biliary tree. CCA has a poor prognosis, its clinical management remains challenging, and effective treatments are lacking....
9.
Ferlier T, Coulouarn C
Cells . 2022 Dec; 11(24). PMID: 36552821
Regulation of gene expression takes a central place in normal cells to maintain tissue homeostasis but also in cancer cells to respond to intra- and extra-cellular stimuli, such as therapeutic...
10.
Boisteau E, Posseme C, Di Modugno F, Edeline J, Coulouarn C, Hrstka R, et al.
Oncogene . 2022 Sep; 41(42):4673-4685. PMID: 36068336
Most of the organs of the digestive tract comprise secretory epithelia that require specialized molecular machines to achieve their functions. As such anterior gradient (AGR) proteins, which comprise AGR1, AGR2,...