David S Moss
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Explore the profile of David S Moss including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
548
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Recent Articles
1.
Stejskal L, Kalemera M, Lewis C, Palor M, Walker L, Daviter T, et al.
Elife
. 2022 Jul;
11.
PMID: 35796426
E1 and E2 (E1E2), the fusion proteins of Hepatitis C Virus (HCV), are unlike that of any other virus yet described, and the detailed molecular mechanisms of HCV entry/fusion remain...
2.
Szkop K, Moss D, Nobeli I
Bioinformatics
. 2020 Oct;
37(10):1461-1464.
PMID: 33051680
Motivation: We present flexible Modeling of Alternative PolyAdenylation (flexiMAP), a new beta-regression-based method implemented in R, for discovering differential alternative polyadenylation events in standard RNA-seq data. Results: We show, using...
3.
Stejskal L, Lees W, Moss D, Palor M, Bingham R, Shepherd A, et al.
PLoS Comput Biol
. 2020 Feb;
16(2):e1007710.
PMID: 32109245
The glycoproteins of hepatitis C virus, E1E2, are unlike any other viral fusion machinery yet described, and are the current focus of immunogen design in HCV vaccine development; thus, making...
4.
Savva C, Clark A, Naylor C, Popoff M, Moss D, Basak A, et al.
Nat Commun
. 2019 Jun;
10(1):2641.
PMID: 31201325
Epsilon toxin (Etx), a potent pore forming toxin (PFT) produced by Clostridium perfringens, is responsible for the pathogenesis of enterotoxaemia of ruminants and has been suggested to play a role...
5.
Hart D, Uzun N, Skelton S, Kakoschke A, Househam J, Moss D, et al.
Haematologica
. 2018 Sep;
104(3):599-608.
PMID: 30266735
Single missense mutations in the gene encoding the coagulation protein factor VIII give rise predominantly to non-severe hemophilia A. Despite only a single amino acid sequence difference between the replacement,...
6.
Szkop K, Cooke P, Humphries J, Kalna V, Moss D, Schuster E, et al.
Front Mol Neurosci
. 2017 Sep;
10:279.
PMID: 28955198
We present here the hypothesis that alternative poly-adenylation (APA) is dysregulated in the brains of individuals affected by Autism Spectrum Disorder (ASD), due to disruptions in the calcium signaling networks....
7.
Lees W, Stejskal L, Moss D, Shepherd A
Front Immunol
. 2017 Mar;
8:143.
PMID: 28261207
In studying the binding of host antibodies to the surface antigens of pathogens, the structural and functional characterization of antibody-antigen complexes by X-ray crystallography and binding assay is important. However,...
8.
Shepherd A, Skelton S, Sansom C, Gomez K, Moss D, Hart D
Br J Haematol
. 2014 Sep;
168(3):413-20.
PMID: 25244644
Over 500 missense F8 mutations have been reported to cause non-severe haemophilia A. Some F8 genotypes appear to confer a higher risk of inhibitor formation than others and individuals with...
9.
Pentiah K, Lees W, Moss D, Shepherd A
Glycobiology
. 2014 Sep;
25(1):124-32.
PMID: 25227423
The extent of the role of N-linked glycans (N-glycans) in shielding influenza A hemagglutinin (HA) against host antibodies has proved controversial, with different authors making widely different assumptions. One common...
10.
Yelland T, Naylor C, Bagoban T, Savva C, Moss D, McClane B, et al.
J Mol Biol
. 2014 Jul;
426(18):3134-3147.
PMID: 25020226
CPE (Clostridium perfringens enterotoxin) is the major virulence determinant for C. perfringens type-A food poisoning, the second most common bacterial food-borne illness in the UK and USA. After binding to...