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Clare E Sansom

Explore the profile of Clare E Sansom including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 56
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Recent Articles
1.
Sansom C
Ecancermedicalscience . 2014 Dec; 8:483. PMID: 25525461
The ninth conference of the International Institute for Anticancer Research, held in Sithonia, Greece in October 2014, included over 700 abstracts presented in 79 separate sessions and featured a wide...
2.
Shepherd A, Skelton S, Sansom C, Gomez K, Moss D, Hart D
Br J Haematol . 2014 Sep; 168(3):413-20. PMID: 25244644
Over 500 missense F8 mutations have been reported to cause non-severe haemophilia A. Some F8 genotypes appear to confer a higher risk of inhibitor formation than others and individuals with...
3.
Halling-Brown M, Pappalardo F, Rapin N, Zhang P, Alemani D, Emerson A, et al.
Philos Trans A Math Phys Eng Sci . 2010 May; 368(1920):2799-815. PMID: 20439274
The ultimate aim of the EU-funded ImmunoGrid project is to develop a natural-scale model of the human immune system-that is, one that reflects both the diversity and the relative proportions...
4.
Halling-Brown M, Shaban R, Frampton D, Sansom C, Davies M, Flower D, et al.
Mol Immunol . 2009 Jun; 46(13):2699-705. PMID: 19560824
T cell activation is the final step in a complex pathway through which pathogen-derived peptide fragments can elicit an immune response. For it to occur, peptides must form stable complexes...
5.
Halling-Brown M, Moss D, Sansom C, Shepherd A
Philos Trans A Math Phys Eng Sci . 2009 Jun; 367(1898):2705-16. PMID: 19487206
We have developed a computational Grid that enables us to exploit through a single interface a range of local, national and international resources. It insulates the user as far as...
6.
Halling-Brown M, Sansom C, Davies M, Titball R, Moss D
Trends Immunol . 2008 Jul; 29(8):374-9. PMID: 18603471
For many infectious diseases, protective immunity can be elicited by vaccination with pathogen-derived proteins. Peptides derived from these proteins are bound to major histocompatibility complex (MHC) molecules and presented to...
7.
Davies M, Lamikanra A, Sansom C, Flower D, Moss D, Travers P
Mol Immunol . 2007 Sep; 45(4):1063-70. PMID: 17870168
Human leukocyte antigen (HLA)-DM is a critical participant in antigen presentation that catalyzes the dissociation of the Class II-associated Invariant chain-derived Peptide (CLIP) from the major histocompatibility complex (MHC) Class...
8.
Davies M, Sansom C, Beazley C, Moss D
Mol Med . 2004 Jun; 9(9-12):220-5. PMID: 15208743
Antigenic peptide is presented to a T-cell receptor through the formation of a stable complex with a Major Histocompatibility Complex (MHC) molecule. Various predictive algorithms have been developed to estimate...