David S Askew
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Explore the profile of David S Askew including associated specialties, affiliations and a list of published articles.
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48
Citations
4138
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Recent Articles
1.
Guirao-Abad J, Shearer S, Bowden J, Kasprovic D, Grisham C, Ozdemir M, et al.
bioRxiv
. 2025 Jan;
PMID: 39763713
is the etiologic agent of invasive aspergillosis, a life- threatening fungal pneumonia that is initiated by the inhalation of conidia (spores) into the lung. If the conidia are not cleared,...
2.
Cox C, Askew D
J Microbiol Biol Educ
. 2023 Dec;
24(3).
PMID: 38108000
Undergraduate students in the biomedical sciences are mostly unaware of how clinical microbiology laboratories handle suspected agents of bioterrorism or emerging infectious diseases. The Public Health Security Bioterrorism Preparedness and...
3.
Guirao-Abad J, Weichert M, Askew D
Curr Res Microb Sci
. 2022 Aug;
3:100119.
PMID: 35909601
One of the most potent opportunistic fungal pathogens of humans is , an environmental mold that causes a life-threatening pneumonia with a high rate of morbidity and mortality. Despite advances...
4.
Guirao-Abad J, Weichert M, Luengo-Gil G, Wong S, Aimanianda V, Grisham C, et al.
mBio
. 2021 Oct;
12(5):e0273521.
PMID: 34663092
Aspergillus fumigatus is a human-pathogenic mold that extracts nutrients from the environment or from host tissues by secreting hydrolytic enzymes. The ability of A. fumigatus to adjust secretion levels in...
5.
Guirao-Abad J, Weichert M, Albee A, Deck K, Askew D
mSphere
. 2020 Oct;
5(5).
PMID: 33087521
The unfolded protein response (UPR) is a signaling network that maintains homeostasis of the endoplasmic reticulum (ER). In the human-pathogenic fungus , the UPR is initiated by activation of an...
6.
Weichert M, Guirao-Abad J, Aimanianda V, Krishnan K, Grisham C, Snyder P, et al.
mBio
. 2020 Jun;
11(3).
PMID: 32487759
Many species of pathogenic fungi deploy the unfolded protein response (UPR) to expand the folding capacity of the endoplasmic reticulum (ER) in proportion to the demand for virulence-related proteins that...
7.
Raj S, Krishnan K, Askew D, Helynck O, Suzanne P, Lesnard A, et al.
Antimicrob Agents Chemother
. 2015 Dec;
60(3):1438-49.
PMID: 26666917
In a search for new antifungal compounds, we screened a library of 4,454 chemicals for toxicity against the human fungal pathogen Aspergillus fumigatus. We identified sr7575, a molecule that inhibits...
8.
Krishnan K, Askew D
Fungal Biol Rev
. 2014 Nov;
28(2-3):29-35.
PMID: 25419229
The gateway to the secretory pathway is the endoplasmic reticulum (ER), an organelle that is responsible for the accurate folding, post-translational modification and final assembly of up to a third...
9.
Askew D, Kontoyiannis D, Clemons K
Mycopathologia
. 2014 Oct;
178(5-6):321-4.
PMID: 25287755
No abstract available.
10.
Krishnan K, Ren Z, Losada L, Nierman W, Lu L, Askew D
BMC Genomics
. 2014 Feb;
15:159.
PMID: 24568630
Background: The unfolded protein response (UPR) is a network of intracellular signaling pathways that supports the ability of the secretory pathway to maintain a balance between the load of proteins...