David S Askew
Overview
Explore the profile of David S Askew including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
48
Citations
4138
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
12.
Krishnan K, Askew D
Virulence
. 2013 Nov;
5(2):334-40.
PMID: 24189125
Aspergillus fumigatus is an opportunistic pathogen that is responsible for a life-threatening fungal infection known as invasive aspergillosis. Current therapies for the treatment of this disease continue to be associated...
13.
Powers-Fletcher M, Feng X, Krishnan K, Askew D
PLoS One
. 2013 Jun;
8(6):e66741.
PMID: 23785510
Small GTPases of the Rab family are master regulators of membrane trafficking, responsible for coordinating the sorting, packaging and delivery of membrane-bound vesicles to specific sites within eukaryotic cells. The...
14.
Jambunathan K, Watson D, Najvar L, Wiederhold N, Kirkpatrick W, Patterson T, et al.
Med Mycol
. 2013 Jan;
51(6):592-602.
PMID: 23356446
Improved diagnostics are needed to detect invasive pulmonary aspergillosis, a life-threatening infection caused by the pathogenic fungus Aspergillus fumigatus. We are investigating secreted fungal proteases as novel biomarkers for the...
15.
Krishnan K, Feng X, Powers-Fletcher M, Bick G, Richie D, Woollett L, et al.
Eukaryot Cell
. 2013 Jan;
12(4):512-9.
PMID: 23355008
Proteins that are destined for release outside the eukaryotic cell, insertion into the plasma membrane, or delivery to intracellular organelles are processed and folded in the endoplasmic reticulum (ER). An...
16.
Klionsky D, Abdalla F, Abeliovich H, Abraham R, Acevedo-Arozena A, Adeli K, et al.
Autophagy
. 2012 Sep;
8(4):445-544.
PMID: 22966490
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered...
17.
Gravelat F, Askew D, Sheppard D
Methods Mol Biol
. 2012 Feb;
845:119-30.
PMID: 22328371
The construction of a fungal strain that lacks a specific gene product is often accomplished by replacing the gene of interest with a selection marker using site-specific recombination. Transformation of...
18.
Powers-Fletcher M, Jambunathan K, Brewer J, Krishnan K, Feng X, Galande A, et al.
PLoS One
. 2011 Dec;
6(12):e28865.
PMID: 22163332
Calnexin is a membrane-bound lectin chaperone in the endoplasmic reticulum (ER) that is part of a quality control system that promotes the accurate folding of glycoproteins entering the secretory pathway....
19.
Feng X, Krishnan K, Richie D, Aimanianda V, Hartl L, Grahl N, et al.
PLoS Pathog
. 2011 Oct;
7(10):e1002330.
PMID: 22028661
Endoplasmic reticulum (ER) stress is a condition in which the protein folding capacity of the ER becomes overwhelmed by an increased demand for secretion or by exposure to compounds that...
20.
Watson D, Jambunathan K, Askew D, Kodukula K, Galande A
Biotechniques
. 2011 Aug;
51(2):95-104.
PMID: 21806553
Proteases are candidate biomarkers and therapeutic targets for many diseases. Sensitive and robust techniques are needed to quantify proteolytic activities within the complex biological milieu. We hypothesized that a combinatorial...