David P Bazett-Jones
Overview
Explore the profile of David P Bazett-Jones including associated specialties, affiliations and a list of published articles.
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56
Citations
4441
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Recent Articles
1.
Salsman J, Rapkin L, Margam N, Duncan R, Bazett-Jones D, Dellaire G
Cell Death Dis
. 2017 Mar;
8(3):e2724.
PMID: 28358373
The promyelocytic leukemia protein (PML) is expressed in most normal human tissues and forms nuclear bodies (NBs) that have roles in gene regulation and cellular processes such as DNA repair,...
2.
Hassan-Zadeh V, Rugg-Gunn P, Bazett-Jones D
Chromosoma
. 2017 Jan;
126(5):605-614.
PMID: 28084535
Epiblast stem cells (EpiSCs), which are pluripotent cells isolated from early post-implantation mouse embryos (E5.5), show both similarities and differences compared to mouse embryonic stem cells (mESCs), isolated earlier from...
3.
FANCD2 limits BLM-dependent telomere instability in the alternative lengthening of telomeres pathway
Root H, Larsen A, Komosa M, Al-Azri F, Li R, Bazett-Jones D, et al.
Hum Mol Genet
. 2016 Jul;
25(15):3255-3268.
PMID: 27427384
Fanconi anemia and Bloom syndrome are genomic instability syndromes caused by mutations in proteins that participate in overlapping DNA repair and replication pathways. Here, we show that the monoubiquitinated form...
4.
Anchel D, Ching R, Cotton R, Li R, Bazett-Jones D
Sci Rep
. 2016 Jul;
6:29191.
PMID: 27389808
Gene loci make specific associations with compartments of the nucleus (e.g. the nuclear envelope, nucleolus, and transcription factories) and this association may determine or reflect a mechanism of genetic control....
5.
Novo C, Tang C, Ahmed K, Djuric U, Fussner E, Mullin N, et al.
Genes Dev
. 2016 Apr;
30(9):1101-15.
PMID: 27125671
An open and decondensed chromatin organization is a defining property of pluripotency. Several epigenetic regulators have been implicated in maintaining an open chromatin organization, but how these processes are connected...
6.
Gallo M, Coutinho F, Vanner R, Gayden T, Mack S, Murison A, et al.
Cancer Cell
. 2015 Dec;
28(6):715-729.
PMID: 26626085
Mutations in the histone 3 variant H3.3 have been identified in one-third of pediatric glioblastomas (GBMs), but not in adult tumors. Here we show that H3.3 is a dynamic determinant...
7.
Rapkin L, Ahmed K, Dulev S, Li R, Kimura H, Ishov A, et al.
Epigenetics Chromatin
. 2015 Oct;
8:44.
PMID: 26500702
Background: The death domain-associated protein (DAXX) collaborates with accessory proteins to deposit the histone variant H3.3 into mouse telomeric and pericentromeric repeat DNA. Pericentromeric repeats are the main genetic contributor...
8.
Even-Faitelson L, Hassan-Zadeh V, Baghestani Z, Bazett-Jones D
Chromosoma
. 2015 Jul;
125(1):95-110.
PMID: 26223534
Chromatin, once thought to serve only as a means to package DNA, is now recognized as a major regulator of gene activity. As a result of the wide range of...
9.
Swanson E, Rapkin L, Bazett-Jones D, Lawrence J
Nucleus
. 2015 Jun;
6(4):254-60.
PMID: 26107557
Cell senescence, the permanent withdrawal of a cell from the cell cycle, is characterized by dramatic, cytological scale changes to DNA condensation throughout the genome. While prior emphasis has been...
10.
Nott T, Petsalaki E, Farber P, Jervis D, Fussner E, Plochowietz A, et al.
Mol Cell
. 2015 Mar;
57(5):936-947.
PMID: 25747659
Cells chemically isolate molecules in compartments to both facilitate and regulate their interactions. In addition to membrane-encapsulated compartments, cells can form proteinaceous and membraneless organelles, including nucleoli, Cajal and PML...