David L Williams
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Explore the profile of David L Williams including associated specialties, affiliations and a list of published articles.
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331
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11714
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Recent Articles
11.
Rosati D, Pradhan A, van Heck J, Helder L, Jaeger M, Gow N, et al.
J Infect Dis
. 2024 Mar;
230(3):768-777.
PMID: 38446996
The interaction between the Candida albicans cell wall and pattern recognition receptors is crucial for the initiation of host immune responses, which, ultimately, contribute to the clearance of this pathogenic...
12.
Ma Z, Ensley H, Graves B, Kruppa M, Rice P, Lowman D, et al.
Carbohydr Res
. 2024 Feb;
537:109059.
PMID: 38408423
Candida auris is an emerging fungal pathogen that has become a world-wide public health threat. While there have been numerous studies into the nature, composition and structure of the cell...
13.
Torigoe S, Lowman D, Sugiki T, Williams D, Yamasaki S
Genes Cells
. 2024 Feb;
29(4):316-327.
PMID: 38385597
Dectin-1 is a well-characterized C-type lectin receptor involved in anti-fungal immunity through the recognition of polysaccharides; however, molecular mechanisms and outcomes initiated through self-recognition have not been fully understood. Here,...
14.
Keever K, Cui K, Casteel J, Singh S, Hoover D, Williams D, et al.
J Neuroinflammation
. 2024 Jan;
21(1):3.
PMID: 38178134
Background: The involvement of the autonomic nervous system in the regulation of inflammation is an emerging concept with significant potential for clinical applications. Recent studies demonstrate that stimulating the vagus...
15.
Marinho Y, Villarreal E, Aboagye S, Williams D, Sun J, Silva C, et al.
Front Immunol
. 2023 Nov;
14:1254762.
PMID: 37908354
Schistosomiasis-associated Pulmonary Arterial Hypertension (Sch-PAH) is a life-threatening complication of chronic infection that can lead to heart failure and death. During PAH, the expansion of apoptosis-resistant endothelial cells (ECs) has...
16.
McBride M, Stothers C, Fensterheim B, Caja K, Owen A, Hernandez A, et al.
J Leukoc Biol
. 2023 Oct;
115(2):358-373.
PMID: 37793181
Exposure to pathogen-associated molecular patterns (PAMPs) induces an augmented, broad-spectrum antimicrobial response to subsequent infection, a phenomenon termed innate immune memory. This study examined the effects of treatment with β-glucan,...
17.
Petukhova V, Aboagye S, Ardini M, Lullo R, Fata F, Byrne M, et al.
Nat Commun
. 2023 Jun;
14(1):3737.
PMID: 37349300
Only praziquantel is available for treating schistosomiasis, a disease affecting more than 200 million people. Praziquantel-resistant worms have been selected for in the lab and low cure rates from mass...
18.
Chaumond E, Peron S, Daniel N, Le Gouar Y, Guedon E, Williams D, et al.
Front Immunol
. 2023 Jun;
14:1138539.
PMID: 37325649
Introduction: The mechanisms underlying innate immune memory (trained immunity) comprise epigenetic reprogramming of transcriptional pathways associated with alterations of intracellular metabolism. While the mechanisms of innate immune memory carried out...
19.
Hatinguais R, Kay M, Salazar F, Conn D, Williams D, Cook P, et al.
Microbiol Spectr
. 2023 May;
11(3):e0113523.
PMID: 37158741
Fc-C-type lectin receptor (Fc-CTLRs) probes are soluble chimeric proteins constituted of the extracellular domain of a CTLR fused with the constant fraction (Fc) of the human IgG. These probes are...
20.
Smith M, Alt T, Williams D, Moran G
Biochemistry
. 2023 Apr;
62(9):1497-1508.
PMID: 37071546
Thioredoxin/glutathione reductase from (SmTGR) catalyzes the reduction of both oxidized thioredoxin and glutathione with electrons from reduced nicotinamide adenine dinucleotide phosphate (NADPH). SmTGR is a drug target for the treatment...