David Jarrossay
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Explore the profile of David Jarrossay including associated specialties, affiliations and a list of published articles.
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45
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5282
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Recent Articles
1.
Kramer M, Mele F, Jovic S, Fernandez B, Jarrossay D, Low J, et al.
J Clin Invest
. 2025 Jan;
135(2.
PMID: 39817450
Autoimmune hepatitis (AIH) is a rare chronic inflammatory liver disease characterized by the presence of autoantibodies, including those targeting O-phosphoseryl-tRNA:selenocysteine-tRNA synthase (SepSecS), also known as soluble liver antigen (SLA). Anti-SepSecS...
2.
Paparoditis P, Fruehwirth A, Bevc K, Low J, Jerak J, Terzaghi L, et al.
Eur J Immunol
. 2024 Jul;
54(10):e2451045.
PMID: 39031535
Efficient identification of human monoclonal antibodies targeting specific antigenic sites is pivotal for advancing vaccines and immunotherapies against infectious diseases and cancer. Existing screening techniques, however, limit our ability to...
3.
Martini V, Silvestri Y, Ciurea A, Moller B, Danelon G, Flamigni F, et al.
RMD Open
. 2024 Feb;
10(1).
PMID: 38395454
Objectives: Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease affecting mainly the axial skeleton. Peripheral involvement (arthritis, enthesitis and dactylitis) and extra-musculoskeletal manifestations, including uveitis, psoriasis and bowel inflammation,...
4.
Melgrati S, Radice E, Ameti R, Hub E, Thelen S, Pelczar P, et al.
PLoS Biol
. 2023 May;
21(5):e3002111.
PMID: 37159457
Atypical chemokine receptors (ACKRs) scavenge chemokines and can contribute to gradient formation by binding, internalizing, and delivering chemokines for lysosomal degradation. ACKRs do not couple to G-proteins and fail to...
5.
Muri J, Cecchinato V, Cavalli A, Shanbhag A, Matkovic M, Biggiogero M, et al.
Nat Immunol
. 2023 Mar;
24(4):604-611.
PMID: 36879067
Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse symptoms, which can persist for months. While antiviral antibodies are protective, those targeting interferons and other immune factors are...
6.
Bianchini F, Crivelli V, Abernathy M, Guerra C, Palus M, Muri J, et al.
Sci Immunol
. 2023 Jan;
8(81):eade0958.
PMID: 36701425
Emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants diminishes the efficacy of vaccines and antiviral monoclonal antibodies. Continued development of immunotherapies and vaccine immunogens resilient to viral evolution...
7.
Bianchini F, Crivelli V, Abernathy M, Guerra C, Palus M, Muri J, et al.
bioRxiv
. 2022 Dec;
PMID: 36482967
One Sentence Summary: Broadly cross-reactive antibodies that protect from SARS-CoV-2 variants are revealed by virus coldspot-driven discovery.
8.
Hu M, Notarbartolo S, Foglierini M, Jovic S, Mele F, Jarrossay D, et al.
Eur J Immunol
. 2022 Dec;
53(2):e2250190.
PMID: 36480793
T follicular helper (T ) cells play an essential role in promoting B cell responses and antibody affinity maturation in germinal centers (GC). A subset of memory CD4 T cells...
9.
Low J, Jerak J, Tortorici M, McCallum M, Pinto D, Cassotta A, et al.
Science
. 2022 Jul;
377(6607):735-742.
PMID: 35857703
The coronavirus spike glycoprotein attaches to host receptors and mediates viral fusion. Using a broad screening approach, we isolated seven monoclonal antibodies (mAbs) that bind to all human-infecting coronavirus spike...
10.
Muri J, Cecchinato V, Cavalli A, Shanbhag A, Matkovic M, Biggiogero M, et al.
bioRxiv
. 2022 Jun;
PMID: 35664993
One-sentence Summary: Naturally arising anti-chemokine antibodies associate with favorable COVID-19 and predict lack of long COVID.