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Antonio Lanzavecchia

Explore the profile of Antonio Lanzavecchia including associated specialties, affiliations and a list of published articles. Areas
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Articles 226
Citations 28174
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Recent Articles
1.
Kramer M, Mele F, Jovic S, Fernandez B, Jarrossay D, Low J, et al.
J Clin Invest . 2025 Jan; 135(2. PMID: 39817450
Autoimmune hepatitis (AIH) is a rare chronic inflammatory liver disease characterized by the presence of autoantibodies, including those targeting O-phosphoseryl-tRNA:selenocysteine-tRNA synthase (SepSecS), also known as soluble liver antigen (SLA). Anti-SepSecS...
2.
Ceraolo M, Leccese M, Cassotta A, Triolo S, Bombaci M, Coluccio E, et al.
Eur J Immunol . 2024 Dec; 55(2):e202451404. PMID: 39663678
Identifying activated T lymphocytes and differentiating antigen-specific from bystander T cells is crucial for understanding adaptive immune responses. This study investigates the efficacy of activation-induced markers (AIMs) in distinguishing these...
3.
Rosen L, Tortorici M, De Marco A, Pinto D, Foreman W, Taylor A, et al.
Cell . 2024 Oct; 187(25):7196-7213.e26. PMID: 39383863
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolution has resulted in viral escape from clinically authorized monoclonal antibodies (mAbs), creating a need for mAbs that are resilient to epitope diversification....
4.
Taylor R, Xiao S, Carias A, McRaven M, Thakkar D, Arainga M, et al.
AIDS Res Hum Retroviruses . 2024 Aug; 40(11):637-648. PMID: 39104250
Neutralizing monoclonal antibodies hold great potential for prevention of human immunodeficiency virus (HIV) acquisition. IgG is the most abundant antibody in human serum, has a long half-life, and potent effector...
5.
Paparoditis P, Fruehwirth A, Bevc K, Low J, Jerak J, Terzaghi L, et al.
Eur J Immunol . 2024 Jul; 54(10):e2451045. PMID: 39031535
Efficient identification of human monoclonal antibodies targeting specific antigenic sites is pivotal for advancing vaccines and immunotherapies against infectious diseases and cancer. Existing screening techniques, however, limit our ability to...
6.
Addetia A, Piccoli L, Case J, Park Y, Beltramello M, Guarino B, et al.
Nature . 2023 Aug; 621(7979):592-601. PMID: 37648855
Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots in the receptor-binding domain (RBD) of the spike protein. The effects of these mutations on viral infection and transmission...
7.
Momont C, Dang H, Zatta F, Hauser K, Wang C, di Iulio J, et al.
Nature . 2023 Jul; 619(7970):E50. PMID: 37407829
No abstract available.
8.
Momont C, Dang H, Zatta F, Hauser K, Wang C, di Iulio J, et al.
Nature . 2023 May; 618(7965):590-597. PMID: 37258672
Rapidly evolving influenza A viruses (IAVs) and influenza B viruses (IBVs) are major causes of recurrent lower respiratory tract infections. Current influenza vaccines elicit antibodies predominantly to the highly variable...
9.
Ingelfinger F, Kramer M, Lutz M, Widmer C, Piccoli L, Kreutmair S, et al.
Neurol Neuroimmunol Neuroinflamm . 2023 Feb; 10(2). PMID: 36754834
Background And Objectives: Myasthenia gravis (MG) can in rare cases be an autoimmune phenomenon associated with hematologic malignancies such as chronic lymphocytic leukemia (CLL). It is unclear whether in patients...
10.
Addetia A, Piccoli L, Case J, Park Y, Beltramello M, Guarino B, et al.
bioRxiv . 2023 Jan; PMID: 36711984
Currently circulating SARS-CoV-2 variants acquired convergent mutations at receptor-binding domain (RBD) hot spots. Their impact on viral infection, transmission, and efficacy of vaccines and therapeutics remains poorly understood. Here, we...