Antonino Cassotta
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Explore the profile of Antonino Cassotta including associated specialties, affiliations and a list of published articles.
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20
Citations
1471
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Recent Articles
1.
Kramer M, Mele F, Jovic S, Fernandez B, Jarrossay D, Low J, et al.
J Clin Invest
. 2025 Jan;
135(2.
PMID: 39817450
Autoimmune hepatitis (AIH) is a rare chronic inflammatory liver disease characterized by the presence of autoantibodies, including those targeting O-phosphoseryl-tRNA:selenocysteine-tRNA synthase (SepSecS), also known as soluble liver antigen (SLA). Anti-SepSecS...
2.
Ceraolo M, Leccese M, Cassotta A, Triolo S, Bombaci M, Coluccio E, et al.
Eur J Immunol
. 2024 Dec;
55(2):e202451404.
PMID: 39663678
Identifying activated T lymphocytes and differentiating antigen-specific from bystander T cells is crucial for understanding adaptive immune responses. This study investigates the efficacy of activation-induced markers (AIMs) in distinguishing these...
3.
Paparoditis P, Fruehwirth A, Bevc K, Low J, Jerak J, Terzaghi L, et al.
Eur J Immunol
. 2024 Jul;
54(10):e2451045.
PMID: 39031535
Efficient identification of human monoclonal antibodies targeting specific antigenic sites is pivotal for advancing vaccines and immunotherapies against infectious diseases and cancer. Existing screening techniques, however, limit our ability to...
4.
Franco F, Bevilacqua A, Wu R, Kao K, Lin C, Rousseau L, et al.
Sci Immunol
. 2023 Sep;
8(87):eadf7579.
PMID: 37738363
Mitophagy, a central process guarding mitochondrial quality, is commonly impaired in human diseases such as Parkinson's disease, but its impact in adaptive immunity remains unclear. The differentiation and survival of...
5.
Marzi R, Bassi J, Silacci-Fregni C, Bartha I, Muoio F, Culap K, et al.
iScience
. 2022 Dec;
26(1):105726.
PMID: 36507220
Memory B cells (MBCs) generate rapid antibody responses upon secondary encounter with a pathogen. Here, we investigated the kinetics, avidity, and cross-reactivity of serum antibodies and MBCs in 155 SARS-CoV-2...
6.
Hu M, Notarbartolo S, Foglierini M, Jovic S, Mele F, Jarrossay D, et al.
Eur J Immunol
. 2022 Dec;
53(2):e2250190.
PMID: 36480793
T follicular helper (T ) cells play an essential role in promoting B cell responses and antibody affinity maturation in germinal centers (GC). A subset of memory CD4 T cells...
7.
Marzi R, Bassi J, Silacci-Fregni C, Bartha I, Muoio F, Culap K, et al.
bioRxiv
. 2022 Oct;
PMID: 36203553
Memory B cells (MBCs) generate rapid antibody responses upon secondary encounter with a pathogen. Here, we investigated the kinetics, avidity and cross-reactivity of serum antibodies and MBCs in 155 SARS-CoV-2...
8.
Low J, Jerak J, Tortorici M, McCallum M, Pinto D, Cassotta A, et al.
Science
. 2022 Jul;
377(6607):735-742.
PMID: 35857703
The coronavirus spike glycoprotein attaches to host receptors and mediates viral fusion. Using a broad screening approach, we isolated seven monoclonal antibodies (mAbs) that bind to all human-infecting coronavirus spike...
9.
Phad G, Pinto D, Foglierini M, Akhmedov M, Rossi R, Malvicini E, et al.
Nat Immunol
. 2022 Jun;
23(7):1076-1085.
PMID: 35761085
Memory B cells persist for a lifetime and rapidly differentiate into antibody-producing plasmablasts and plasma cells upon antigen re-encounter. The clonal relationship and evolution of memory B cells and circulating...
10.
Cossarizza A, Chang H, Radbruch A, Abrignani S, Addo R, Akdis M, et al.
Eur J Immunol
. 2021 Dec;
51(12):2708-3145.
PMID: 34910301
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when performing flow cytometry experiments and includes comprehensive sections describing phenotypes and functional assays of all major...