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David I R Holmes

Explore the profile of David I R Holmes including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 342
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Recent Articles
1.
Holmes D, Zachary I
Cell Signal . 2008 Jan; 20(3):569-79. PMID: 18164591
Stanniocalcin-1 (STC-1) is a glycoprotein hormone originally identified as a regulator of calcium and phosphate homeostasis in bony fish. Up-regulation of the mammalian homolog in numerous gene profiling studies of...
2.
Stannard A, Khurana R, Evans I, Sofra V, Holmes D, Zachary I
Arterioscler Thromb Vasc Biol . 2006 Dec; 27(3):494-502. PMID: 17170373
Objective: The regulation of endothelial cell adhesion molecules (CAMs) by vascular endothelial growth factor (VEGF) was investigated in cell cultures and in a rabbit model of atherogenic neointima formation. Methods...
3.
Holmes D, Zachary I
Genome Biol . 2005 Feb; 6(2):209. PMID: 15693956
Vascular endothelial growth factors (VEGFs) are a family of secreted polypeptides with a highly conserved receptor-binding cystine-knot structure similar to that of the platelet-derived growth factors. VEGF-A, the founding member...
4.
Cheng L, Jia H, Lohr M, Bagherzadeh A, Holmes D, Selwood D, et al.
J Biol Chem . 2004 May; 279(29):30654-61. PMID: 15126502
Vascular endothelial growth factor (VEGF) displays neurotrophic and neuroprotective activities, but the mechanisms underlying these effects have not been defined. Neuropilin-1 (NP-1) is a receptor for VEGF165 and placental growth...
5.
Holmes D, Zachary I
FEBS Lett . 2004 Jan; 557(1-3):93-8. PMID: 14741347
Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family that binds specifically to Flt-1. The biological roles of PlGF and Flt-1 have not yet...
6.
Wang Q, Holmes D, Powell S, Lu Q, Waxman J
Cancer Lett . 2001 Dec; 175(1):63-9. PMID: 11734337
A PCR-based subtractive hybridisation technique was used to identify genes involved in stromal-epithelial interactions in prostate cancer. Eight genes were identified as being differentially expressed in benign prostatic fibroblast cells...