David A Bernlohr
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Explore the profile of David A Bernlohr including associated specialties, affiliations and a list of published articles.
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124
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4228
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Recent Articles
1.
Fish S, Halley C, Dileepan M, Hertzel A, Dickey D, Bernlohr D
Biochem Biophys Res Commun
. 2025 Jan;
749:151346.
PMID: 39855040
Adipose is a complex tissue comprised of adipocytes, immune cells, endothelial and progenitor stem cells. In humans, there are at least nine defined adipose depots, each containing variable numbers of...
2.
Monroe T, Hertzel A, Dickey D, Hagen T, Santibanez S, Berdaweel I, et al.
Aging Cell
. 2024 Oct;
24(1):e14367.
PMID: 39394673
Lipid enals are electrophilic products of lipid peroxidation that induce genotoxic and proteotoxic stress by covalent modification of DNA and proteins, respectively. As lipid enals accumulate to substantial amounts in...
3.
Jang I, Kruglov V, Cholensky S, Smith D, Carey A, Bai S, et al.
bioRxiv
. 2024 Oct;
PMID: 39386655
Age-related susceptibility to sepsis and endotoxemia is poorly defined, although hyperactivation of the immune system and the expansion of the visceral adipose as an immunological reservoir are underlying features. Macrophages...
4.
Shih W, Jang I, Kruglov V, Dickey D, Cholensky S, Bernlohr D, et al.
Immun Ageing
. 2024 Aug;
21(1):57.
PMID: 39187841
Background: Aging is a complex biological process characterized by obesity and immunosenescence throughout the organism. Immunosenescence involves a decline in immune function and the increase in chronic-low grade inflammation, called...
5.
Suryadevara V, Hudgins A, Rajesh A, Pappalardo A, Karpova A, Dey A, et al.
Nat Rev Mol Cell Biol
. 2024 Jun;
25(12):1001-1023.
PMID: 38831121
Once considered a tissue culture-specific phenomenon, cellular senescence has now been linked to various biological processes with both beneficial and detrimental roles in humans, rodents and other species. Much of...
6.
Su H, Guo H, Qiu X, Lin T, Qin C, Celio G, et al.
Nat Commun
. 2023 Dec;
14(1):8231.
PMID: 38086875
No abstract available.
7.
Su H, Guo H, Qiu X, Lin T, Qin C, Celio G, et al.
Nat Commun
. 2023 Oct;
14(1):6729.
PMID: 37872178
Mitochondrial function is vital for energy metabolism in thermogenic adipocytes. Impaired mitochondrial bioenergetics in brown adipocytes are linked to disrupted thermogenesis and energy balance in obesity and aging. Phospholipid cardiolipin...
8.
Ruskovska T, Bernlohr D
Biomedicines
. 2023 Sep;
11(9).
PMID: 37761000
Obesity-induced insulin resistance is among the key factors in the development of type 2 diabetes, atherogenic dyslipidemia and cardiovascular disease. Adipose tissue plays a key role in the regulation of...
9.
Olivieri C, Wang Y, Walker C, Subrahmanian M, Ha K, Bernlohr D, et al.
bioRxiv
. 2023 Sep;
PMID: 37745542
Allosteric cooperativity between ATP and substrates is a prominent characteristic of the cAMP-dependent catalytic (C) subunit of protein kinase A (PKA). Not only this long-range synergistic action is involved in...
10.
Huang Y, Hertzel A, Fish S, Halley C, Bohm E, Martinez H, et al.
Diabetes
. 2023 Jun;
72(11):1560-1573.
PMID: 37347719
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