David-Alexandre Gross
Overview
Explore the profile of David-Alexandre Gross including associated specialties, affiliations and a list of published articles.
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26
Citations
608
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Recent Articles
1.
Jauze L, Vie M, Miagoux Q, Rossiaud L, Vidal P, Montalvo-Romeral V, et al.
JCI Insight
. 2024 May;
9(11).
PMID: 38753465
Glycogen storage disease type III (GSDIII) is a rare metabolic disorder due to glycogen debranching enzyme (GDE) deficiency. Reduced GDE activity leads to pathological glycogen accumulation responsible for impaired hepatic...
2.
Gross D, Tedesco N, Leborgne C, Ronzitti G
Front Immunol
. 2022 Apr;
13:857276.
PMID: 35464422
One of the major goals of gene transfer is to achieve long-term expression of therapeutic transgenes in terminally differentiated cells. The extensive clinical experience and the recent approval of Luxturna...
3.
Buscara L, Gross D, Daniele N
J Pers Med
. 2020 Dec;
10(4).
PMID: 33260623
Neuromuscular disorders are a large group of rare pathologies characterised by skeletal muscle atrophy and weakness, with the common involvement of respiratory and/or cardiac muscles. These diseases lead to life-long...
4.
Ronzitti G, Gross D, Mingozzi F
Front Immunol
. 2020 May;
11:670.
PMID: 32362898
Recombinant adeno-associated virus (rAAV) vectors are one of the most promising gene delivery tools. Several features make rAAV vectors an ideal platform for gene transfer. However, the high homology with...
5.
Lalfer M, Chappert P, Carpentier M, Urbain D, Davoust J, Gross D
Front Immunol
. 2019 Apr;
10:521.
PMID: 30941146
Foxp3 regulatory T cells (Tregs) play a major role in acquired immune tolerance to allogenic transplants. Their suppressive activity is thought to require T cell receptor (TCR)-driven antigen recognition; little,...
6.
Gross D, Ghenassia A, Bartolo L, Urbain D, Benkhelifa-Ziyyat S, Lorain S, et al.
J Virol
. 2018 Dec;
93(5).
PMID: 30541847
A key aspect to consider for vaccinal protection is the induction of a local line of defense consisting of nonrecirculating tissue-resident memory T cells (T), in parallel to the generation...
7.
Ghenassia A, Gross D, Lorain S, Tros F, Urbain D, Benkhelifa-Ziyyat S, et al.
Mol Ther
. 2017 Jul;
25(10):2309-2322.
PMID: 28720467
Recombinant adeno-associated viral (rAAV) vectors exhibit interesting properties as vaccine carriers for their ability to induce long-lasting antibody responses. However, rAAV-based vaccines have been suggested to trigger functionally impaired long-term...
8.
Goudin N, Chappert P, Megret J, Gross D, Rocha B, Azogui O
PLoS One
. 2017 Jan;
12(1):e0171373.
PMID: 28129385
[This corrects the article DOI: 10.1371/journal.pone.0157822.].
9.
Trinquand A, Dos Santos N, Tran Quang C, Rocchetti F, Zaniboni B, Belhocine M, et al.
Cancer Discov
. 2016 Jun;
6(9):972-85.
PMID: 27354269
Unlabelled: Cancer onset and progression involves the accumulation of multiple oncogenic hits, which are thought to dominate or bypass the physiologic regulatory mechanisms in tissue development and homeostasis. We demonstrate...
10.
Goudin N, Chappert P, Megret J, Gross D, Rocha B, Azogui O
PLoS One
. 2016 Jun;
11(6):e0157822.
PMID: 27341421
Natural regulatory T (Treg) cells interfere with multiple functions, which are crucial for the development of strong anti-tumour responses. In a model of 4T1 mammary carcinoma, depletion of CD25+Tregs results...