Isabelle Miconnet
Overview
Explore the profile of Isabelle Miconnet including associated specialties, affiliations and a list of published articles.
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16
Citations
530
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Recent Articles
1.
Vigano S, Bellutti Enders F, Miconnet I, Cellerai C, Savoye A, Rozot V, et al.
PLoS Pathog
. 2013 Jul;
9(7):e1003423.
PMID: 23853580
The factors determining the functional avidity and its relationship with the broad heterogeneity of antiviral T cell responses remain partially understood. We investigated HIV-specific CD8 T cell responses in 85...
2.
Miconnet I
Curr Opin HIV AIDS
. 2011 Dec;
7(1):64-70.
PMID: 22156841
Purpose Of Review: To review major findings on the T-cell receptor (TCR) repertoire diversity in response to several viral infections based on conventional methods of PCR, cloning and sequencing and...
3.
Miconnet I, Marrau A, Farina A, Taffe P, Vigano S, Harari A, et al.
J Immunol
. 2011 May;
186(12):7039-49.
PMID: 21555537
Ex vivo analysis of virus-specific CD8 T cell populations by anchored PCR has shown that the CD8 TCR repertoire was less oligoclonal (seven to nine clonotypes per individual epitope) than...
4.
Roger T, Lugrin J, Le Roy D, Goy G, Mombelli M, Koessler T, et al.
Blood
. 2010 Oct;
117(4):1205-17.
PMID: 20956800
Regulated by histone acetyltransferases and deacetylases (HDACs), histone acetylation is a key epigenetic mechanism controlling chromatin structure, DNA accessibility, and gene expression. HDAC inhibitors induce growth arrest, differentiation, and apoptosis...
5.
Miconnet I, Pantaleo G
Vaccine
. 2008 Jun;
26(32):4006-14.
PMID: 18562050
A strategy to improve the immunogenicity of candidate vaccines is to trigger the innate immune system. Triggering of CD40 at the surface of dendritic cells (DC) is essential in the...
6.
Faure O, Graff-Dubois S, Alves P, Cornet S, Duffour M, Scardino A, et al.
Oncol Rep
. 2007 Feb;
17(3):679-85.
PMID: 17273751
The inducible heat shock protein Hsp70 has been described as a tumour antigen being frequently overexpressed in tumours of various histologic origins, with a role in tumourigenicity, as a critical...
7.
Alves P, Faure O, Graff-Dubois S, Cornet S, Bolonakis I, Gross D, et al.
Cancer Immunol Immunother
. 2006 Apr;
55(12):1515-23.
PMID: 16622681
STEAP is a recently identified protein shown to be particularly overexpressed in prostate cancer and also present in numerous human cancer cell lines from prostate, pancreas, colon, breast, testicular, cervical,...
8.
Cornet S, Miconnet I, Menez J, Lemonnier F, Kosmatopoulos K
Vaccine
. 2006 Feb;
24(12):2102-9.
PMID: 16455166
Polyspecific tumor vaccination should offer broad control of tumor cells and reduce the risk of emergence of immune escape variants. Here, we evaluated the capacity of a polypeptide composed of...
9.
Cornet S, Menez-Jamet J, Lemonnier F, Kosmatopoulos K, Miconnet I
Vaccine
. 2005 Nov;
24(11):1880-8.
PMID: 16300869
The use of synthetic peptides derived from tumor-associated Ags is attractive for the development of antitumoral vaccines as far as strong adjuvants are found to render them immunogenic. Here, we...
10.
Roger T, Miconnet I, Schiesser A, Kai H, Miyake K, Calandra T
Biochem J
. 2004 Nov;
387(Pt 2):355-65.
PMID: 15537384
TLR4 (Toll-like receptor 4) is essential for sensing the endotoxin of Gram-negative bacteria. Mutations or deletion of the TLR4 gene in humans or mice have been associated with altered predisposition...