Darren Zuro
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Explore the profile of Darren Zuro including associated specialties, affiliations and a list of published articles.
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11
Citations
94
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Recent Articles
1.
Ghimire H, Madabushi S, Vercellino J, Brooks J, Zuro D, Lim J, et al.
Front Oncol
. 2024 Oct;
14:1414488.
PMID: 39450249
Background: There is a need for therapies that can mitigate bone marrow dysfunction and organ toxicity that occur following myeloablative injury and reduced intensity conditioning regimens used in patients undergoing...
2.
Madabushi S, Fouda R, Ghimire H, Abdelhamid A, Lim J, Vishwasrao P, et al.
Front Oncol
. 2022 Sep;
12:969429.
PMID: 36147914
Sickle cell disease (SCD) is a serious global health problem, and currently, the only curative option is hematopoietic stem cell transplant (HCT). However, myeloablative total body irradiation (TBI)-based HCT is...
3.
Abdelhamid A, Jiang L, Zuro D, Liu A, Madabushi S, Ghimire H, et al.
Front Oncol
. 2022 Aug;
12:941814.
PMID: 35924145
Total marrow irradiation (TMI) has significantly improved radiation conditioning for hematopoietic cell transplantation in hematologic diseases by reducing conditioning-induced toxicities and improving survival outcomes in relapsed/refractory patients. Recently, preclinical three-dimensional...
4.
Brooks J, Zuro D, Song J, Madabushi S, Sanchez J, Guha C, et al.
Int J Radiat Oncol Biol Phys
. 2021 Nov;
112(4):951-963.
PMID: 34767936
Purpose: Recent initial findings suggest that radiation therapy improves blood perfusion and cellular chemotherapy uptake in mice with leukemia. However, the ability of radiation therapy to influence drug accumulation in...
5.
Zuro D, Madabushi S, Brooks J, Chen B, Goud J, Salhotra A, et al.
Int J Radiat Oncol Biol Phys
. 2021 Jun;
111(3):671-683.
PMID: 34119592
Purpose: Total marrow irradiation (TMI) has significantly advanced radiation conditioning for hematopoietic cell transplantation in hematologic malignancies by reducing conditioning-induced toxicities and improving survival outcomes in relapsed/refractory patients. However, the...
6.
Mikhaylova E, Brooks J, Zuro D, Nouizi F, Kujawski M, Madabushi S, et al.
IEEE Access
. 2020 May;
7:143207-143216.
PMID: 32435548
Molecular imaging is becoming essential for precision targeted radiation therapy, yet progress is hindered from a lack of integrated imaging and treatment systems. We report the development of a prototype...
7.
Kujawski M, Sherman M, Hui S, Zuro D, Lee W, Yazaki P, et al.
Oncoimmunology
. 2020 Mar;
9(1):1724052.
PMID: 32117587
While anti-CEA antibodies have no direct effect on CEA-positive tumors, they can be used to direct potent anti-tumor effects as an antibody-IL-2 fusion protein (immunocytokine, ICK), and at the same...
8.
Srideshikan S, Brooks J, Zuro D, Kumar B, Sanchez J, Parra L, et al.
Clin Cancer Res
. 2019 Sep;
25(24):7463-7474.
PMID: 31548348
Purpose: Acute myeloid leukemia (AML) is a highly aggressive form of leukemia, which results in poor survival outcomes. Currently, diagnosis and prognosis are based on invasive single-point bone marrow biopsies...
9.
Zuro D, Vagge S, Broggi S, Agostinelli S, Takahashi Y, Brooks J, et al.
Radiother Oncol
. 2019 Aug;
141:275-282.
PMID: 31421913
Purpose: Total marrow irradiation (TMI) is a highly conformal treatment of the human skeleton structure requiring a high degree of precision and accuracy for treatment delivery. Although many centers worldwide...
10.
Yadav S, Kowolik C, Lin M, Zuro D, Hui S, Riggs A, et al.
Mol Carcinog
. 2018 Sep;
58(1):113-125.
PMID: 30242889
Prostate cancer is one of the most commonly diagnosed cancers and a pressing health challenge in men worldwide. Radiation therapy (RT) is widely considered a standard therapy for advanced as...