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James F Sanchez

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Articles 53
Citations 1612
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Recent Articles
1.
Dona A, Tandoh T, Nigam L, Singer M, Caserta E, Murtadha M, et al.
J Hematol Oncol . 2025 Jan; 18(1):1. PMID: 39828738
Background: Reovirus (RV) is an oncolytic virus with natural tropism for cancer cells. We previously showed that RV administration in multiple myeloma (MM) patients was safe, but disease control associated...
2.
Murtadha M, Park M, Zhu Y, Caserta E, Napolitano O, Tandoh T, et al.
Blood . 2024 Feb; 143(16):1599-1615. PMID: 38394668
Treatment resistance of leukemia stem cells (LSCs) and suppression of the autologous immune system represent major challenges to achieve a cure in acute myeloid leukemia (AML). Although AML blasts generally...
3.
Han Z, Wu X, Qin H, Yuan Y, Schmolze D, Su C, et al.
JCI Insight . 2023 Jul; 8(13). PMID: 37427589
Cutaneous T cell lymphoma (CTCL) is a disfiguring and incurable disease characterized by skin-homing malignant T cells surrounded by immune cells that promote CTCL growth through an immunosuppressive tumor microenvironment...
4.
Dona A, Sanchez J, Palmer J, Synold T, Chiuppesi F, Thomas S, et al.
J Immunol Sci . 2023 Mar; 7(1):9-27. PMID: 36996290
Background: Vaccines for SARS-CoV-2 have been considerably effective in reducing rates of infection and severe COVID-19. However, many patients, especially those who are immunocompromised due to cancer or other factors,...
5.
Murtadha M, Park M, Zhu Y, Caserta E, Dona A, Singer M, et al.
bioRxiv . 2023 Mar; PMID: 36909542
Elimination of drug-resistant leukemia stem cells (LSCs) represents a major challenge to achieve a cure in acute myeloid leukemia (AML). Although AML blasts generally retain high levels of surface CD38...
6.
Stein A, Al Malki M, Yang D, Palmer J, Tsai N, Aldoss I, et al.
Transplant Cell Ther . 2022 Apr; 28(7):368.e1-368.e7. PMID: 35398328
Graft-versus-host disease (GVHD) has remained the main cause of post-transplantation mortality and morbidity after allogeneic hematopoietic cell transplantation (alloHCT), adding significant economic burden and affecting quality of life. It would...
7.
Di Raimondo C, Han Z, Su C, Wu X, Qin H, Sanchez J, et al.
Cancers (Basel) . 2021 Nov; 13(22). PMID: 34831008
Large cell transformation of mycosis fungoides (LCT-MF) occurs in 20-50% of advanced MF and is generally associated with poor response and dismal prognosis. Although different mechanisms have been proposed to...
8.
Han Z, Estephan R, Wu X, Su C, Yuan Y, Qin H, et al.
J Invest Dermatol . 2021 Nov; 142(3 Pt A):603-612.e7. PMID: 34774537
Cutaneous T cell lymphoma (CTCL) is characterized by a background of chronic inflammation, where malignant CTCL cells escape immune surveillance. To study how microRNAs (miRs) regulate T-cell exhaustion, we performed...
9.
Brooks J, Zuro D, Song J, Madabushi S, Sanchez J, Guha C, et al.
Int J Radiat Oncol Biol Phys . 2021 Nov; 112(4):951-963. PMID: 34767936
Purpose: Recent initial findings suggest that radiation therapy improves blood perfusion and cellular chemotherapy uptake in mice with leukemia. However, the ability of radiation therapy to influence drug accumulation in...
10.
Sahebi F, Eikema D, Koster L, Kroger N, Meijer E, van Doesum J, et al.
Transplant Cell Ther . 2021 Sep; 27(12):999.e1-999.e10. PMID: 34543768
Graft-versus-host disease (GVHD) remains among the major causes of treatment failure in patients with multiple myeloma (MM) undergoing allogeneic hematopoietic cell transplantation (allo-HCT). The use of post-transplantation cyclophosphamide (PT-Cy) is...