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Dara L Dickstein

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Articles 54
Citations 2933
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Recent Articles
1.
Castranio E, Varghese M, Argyrousi E, Tripathi K, Soderberg L, Bresnahan E, et al.
bioRxiv . 2025 Mar; PMID: 40060689
Teaser: APP "NFA-Aβ only" mice reveal clinically relevant mechanisms despite the absence of detectable inflammation.
2.
Dickstein D, Zhang R, Ru N, Vozenin M, Perry B, Wang J, et al.
Brain Struct Funct . 2025 Mar; 230(2):41. PMID: 40024988
Evidence shows that ultra-high dose-rate FLASH-radiotherapy (FLASH-RT) provides relative protection against normal tissue complications and functional decrements in the irradiated brain. Past work has shown that radiation-induced cognitive impairment, neuroinflammation...
3.
Hatch K, Lischka F, Wang M, Xu X, Stimpson C, Barvir T, et al.
Sci Rep . 2024 Aug; 14(1):18981. PMID: 39152179
Due to their interactions with the neurovasculature, microglia are implicated in maladaptive responses to hypobaric hypoxia at high altitude (HA). To explore these interactions at HA, pharmacological depletion of microglia...
4.
Dickstein D, Zhang R, Ru N, Vozenin M, Perry B, Wang J, et al.
Res Sq . 2024 Aug; PMID: 39108471
Evidence shows that ultra-high dose-rate FLASH-radiotherapy (FLASH-RT) protects against normal tissue complications and functional decrements in the irradiated brain. Past work has shown that radiation-induced cognitive impairment, neuroinflammation and reduced...
5.
Eyford B, Lazarczyk M, Choi K, Varghese M, Arora H, Kari S, et al.
Sci Rep . 2023 Aug; 13(1):13079. PMID: 37567897
The interplay between AMPA-type glutamate receptors (AMPARs) and major histocompatibility complex class I (MHC-I) proteins in regulating synaptic signaling is a crucial aspect of central nervous system (CNS) function. In...
6.
Lazarczyk M, Eyford B, Varghese M, Arora H, Munro L, Warda T, et al.
Sci Rep . 2023 Apr; 13(1):6448. PMID: 37081001
Major histocompatibility complex class I (MHC-I) proteins are expressed in neurons, where they regulate synaptic plasticity. However, the mechanisms by which MHC-I functions in the CNS remains unknown. Here we...
7.
Alaghband Y, Klein P, Kramar E, Cranston M, Perry B, Shelerud L, et al.
Cell Mol Life Sci . 2023 Jan; 80(1):29. PMID: 36607431
Technological advancements have facilitated the implementation of realistic, terrestrial-based complex 33-beam galactic cosmic radiation simulations (GCR Sim) to now probe central nervous system functionality. This work expands considerably on prior,...
8.
Krishnan B, Natarajan C, Bourne K, Alikhani L, Wang J, Sowa A, et al.
Int J Mol Sci . 2021 Apr; 22(7). PMID: 33915974
The proposed deep space exploration to the moon and later to Mars will result in astronauts receiving significant chronic exposures to space radiation (SR). SR exposure results in multiple neurocognitive...
9.
Perez Garcia G, De Gasperi R, Gama Sosa M, Perez G, Otero-Pagan A, Pryor D, et al.
Acta Neuropathol Commun . 2021 Mar; 9(1):33. PMID: 33648608
Military veterans who experience blast-related traumatic brain injuries often suffer from chronic cognitive and neurobehavioral syndromes. Reports of abnormal tau processing following blast injury have raised concerns that some cases...
10.
Jacot-Descombes S, Keshav N, Dickstein D, Wicinski B, Janssen W, Hiester L, et al.
Mol Autism . 2020 Nov; 11(1):89. PMID: 33203459
Background: Deletion or mutations of SHANK3 lead to Phelan-McDermid syndrome and monogenic forms of autism spectrum disorder (ASD). SHANK3 encodes its eponymous scaffolding protein at excitatory glutamatergic synapses. Altered morphology...